CHEBI:192091 - (−)-N6-(2-phenylisopropyl)adenosine

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ChEBI Name (−)-N6-(2-phenylisopropyl)adenosine
ChEBI ID CHEBI:192091
ChEBI ASCII Name (-)-N(6)-(2-phenylisopropyl)adenosine
Definition A hydrocarbyladenosine in which adenosine is substituted at N-6 by a (2R)-1-phenylpropan-2-yl group. It is a potent adenosine A1 receptor agonist that exhibits neuroprotective and antinociceptive properties.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Kalpana P
Supplier Information
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Formula C19H23N5O4
Net Charge 0
Average Mass 385.424
Monoisotopic Mass 385.17500
InChI InChI=1S/C19H23N5O4/c1-11(7-12-5-3-2-4-6-12)23-17-14-18(21-9-20-17)24(10-22-14)19-16(27)15(26)13(8-25)28-19/h2-6,9-11,13,15-16,19,25-27H,7-8H2,1H3,(H,20,21,23)/t11-,13-,15-,16-,19-/m1/s1
InChIKey RIRGCFBBHQEQQH-SSFGXONLSA-N
SMILES CC(CC1=CC=CC=C1)NC1=C2N=CN(C3OC(CO)C(O)C3O)C2=NC=N1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): adenosine A1 receptor agonist
An agonist at the A1 receptor.
Application(s): neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (−)-N6-(2-phenylisopropyl)adenosine (CHEBI:192091) has functional parent adenosine (CHEBI:16335)
(−)-N6-(2-phenylisopropyl)adenosine (CHEBI:192091) has role adenosine A1 receptor agonist (CHEBI:65057)
(−)-N6-(2-phenylisopropyl)adenosine (CHEBI:192091) has role neuroprotective agent (CHEBI:63726)
(−)-N6-(2-phenylisopropyl)adenosine (CHEBI:192091) is a aromatic amine (CHEBI:33860)
(−)-N6-(2-phenylisopropyl)adenosine (CHEBI:192091) is a benzenes (CHEBI:22712)
(−)-N6-(2-phenylisopropyl)adenosine (CHEBI:192091) is a hydrocarbyladenosine (CHEBI:24909)
(−)-N6-(2-phenylisopropyl)adenosine (CHEBI:192091) is a secondary amino compound (CHEBI:50995)
IUPAC Name
N-[(2R)-1-phenylpropan-2-yl]adenosine
Synonyms Sources
(−)-(phenylisopropyl)adenosine ChemIDplus
(−)-N-(α-methylphenethyl)adenosine ChemIDplus
(−)-N6-(2-phenylisopropyl)adenosine ChEBI
(−)-PIA ChemIDplus
(R)-(−)-N6-phenylisopropyladenosine ChEBI
(R)-(phenylisopropyl)adenosine ChemIDplus
(R)-N-(phenylisopropyl)adenosine ChEBI
(R)-N6-(1-methyl-2-phenylethyl)adenosine ChEBI
(R)-N6-(2-phenylisopropyl)adenosine ChemIDplus
(R)-N6-phenylisopropyladenosine ChemIDplus
(R)-PIA ChemIDplus
L-2-N6-(phenylisopropyl)adenosine ChemIDplus
L-phenylisopropyladenosine ChEBI
L-PIA ChemIDplus
N6-(L-2-phenylisopropyl)adenosine ChEBI
N6-(R)-phenylisopropyladenosine ChEBI
N6-[(R)-1-methyl-2-phenylethyl]adenosine ChEBI
N6-D-phenylisopropyladenosine ChemIDplus
R(−)-N6-(2-phenylisopropyl)adenosine ChEBI
R(−)-PIA ChEBI
R-(−)-N6-2-phenylisopropyladenosine ChEBI
R-(−)-PIA ChEBI
R-phenylisopropyladenosine ChEBI
R-PIA ChEBI
Manual Xrefs Databases
84148 ChemSpider
WO2021099832 Patent
View more database links
Registry Numbers Types Sources
38594-96-6 CAS Registry Number ChemIDplus
4912716 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
08 June 2022