CHEBI:65209 - E-3810 free base

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ChEBI Name E-3810 free base
ChEBI ID CHEBI:65209
Definition A naphthalenecarboxamide obtained from formal condensation of the carboxy group of aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-1-naphthoic acid with methylamine.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C26H25N3O4
Net Charge 0
Average Mass 443.49440
Monoisotopic Mass 443.18451
InChI InChI=1S/C26H25N3O4/c1-28-25(30)19-5-3-4-16-12-17(6-7-18(16)19)33-22-8-11-29-21-14-24(23(31-2)13-20(21)22)32-15-26(27)9-10-26/h3-8,11-14H,9-10,15,27H2,1-2H3,(H,28,30)
InChIKey CUDVHEFYRIWYQD-UHFFFAOYSA-N
SMILES CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): fibroblast growth factor receptor antagonist
An antagonist at the fibroblast growth factor receptor.
vascular endothelial growth factor receptor antagonist
An antagonist at the vascular endothelial growth factor receptor.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing E-3810 free base (CHEBI:65209) has role antineoplastic agent (CHEBI:35610)
E-3810 free base (CHEBI:65209) has role fibroblast growth factor receptor antagonist (CHEBI:63457)
E-3810 free base (CHEBI:65209) has role vascular endothelial growth factor receptor antagonist (CHEBI:65207)
E-3810 free base (CHEBI:65209) is a aromatic ether (CHEBI:35618)
E-3810 free base (CHEBI:65209) is a cyclopropanes (CHEBI:51454)
E-3810 free base (CHEBI:65209) is a naphthalenecarboxamide (CHEBI:48739)
E-3810 free base (CHEBI:65209) is a primary amino compound (CHEBI:50994)
E-3810 free base (CHEBI:65209) is a quinolines (CHEBI:26513)
E-3810 free base (CHEBI:65209) is conjugate base of E-3810(1+) (CHEBI:65208)
Incoming E-3810(1+) (CHEBI:65208) is conjugate acid of E-3810 free base (CHEBI:65209)
IUPAC Name
6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methyl-1-naphthamide
Synonym Source
E-3810 amine ChEBI
Registry Number Type Source
18478470 Reaxys Registry Number Reaxys
Last Modified
06 March 2014