CHEBI:28973 - strychnine

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ChEBI Name strychnine
ChEBI ID CHEBI:28973
Definition A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:9293, CHEBI:26795
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Formula C21H22N2O2
Net Charge 0
Average Mass 334.41160
Monoisotopic Mass 334.16813
InChI InChI=1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1
InChIKey QMGVPVSNSZLJIA-FVWCLLPLSA-N
SMILES [H][C@@]12CC(=O)N3c4ccccc4[C@]45CCN6CC(=CCO1)[C@]([H])(C[C@@]46[H])[C@]2([H])[C@]35[H]
Roles Classification
Biological Role(s): glycine receptor antagonist
An antagonist that blocks glycine receptors.
cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
neurotransmitter agent
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
neurotransmitter agent
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
rodenticide
A substance used to destroy rodent pests.
avicide
A substance used to destroy bird pests (class Aves).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing strychnine (CHEBI:28973) has parent hydride strychnidine (CHEBI:36337)
strychnine (CHEBI:28973) has role avicide (CHEBI:33289)
strychnine (CHEBI:28973) has role cholinergic antagonist (CHEBI:48873)
strychnine (CHEBI:28973) has role glycine receptor antagonist (CHEBI:62754)
strychnine (CHEBI:28973) has role neurotransmitter agent (CHEBI:35942)
strychnine (CHEBI:28973) has role rodenticide (CHEBI:33288)
strychnine (CHEBI:28973) is a monoterpenoid indole alkaloid (CHEBI:65323)
strychnine (CHEBI:28973) is a organic heteroheptacyclic compound (CHEBI:52157)
strychnine (CHEBI:28973) is conjugate base of strychnine(1+) (CHEBI:90700)
Incoming α-colubrine (CHEBI:132696) has functional parent strychnine (CHEBI:28973)
β-colubrine (CHEBI:132697) has functional parent strychnine (CHEBI:28973)
2-hydroxy-3-methoxystrychnine (CHEBI:132705) has functional parent strychnine (CHEBI:28973)
pseudostrychnine (CHEBI:132666) has functional parent strychnine (CHEBI:28973)
strychnine N-oxide (CHEBI:132703) has functional parent strychnine (CHEBI:28973)
strychnine(1+) (CHEBI:90700) is conjugate acid of strychnine (CHEBI:28973)
IUPAC Name
strychnidin-10-one
Synonyms Sources
Strychnin ChemIDplus
Strychnine KEGG COMPOUND
Manual Xrefs Databases
2066 BPDB
2484 DrugCentral
C00001770 KNApSAcK
C00025213 KNApSAcK
C06522 KEGG COMPOUND
Strychnine Wikipedia
SY9 PDBeChem
View more database links
Registry Numbers Types Sources
117894 Gmelin Registry Number Gmelin
52979 Beilstein Registry Number Beilstein
52979 Reaxys Registry Number Reaxys
57-24-9 CAS Registry Number KEGG COMPOUND
57-24-9 CAS Registry Number ChemIDplus
57-24-9 CAS Registry Number NIST Chemistry WebBook
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Last Modified
22 February 2017