CHEBI:83687 - sertaconazole nitrate

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ChEBI Name sertaconazole nitrate
ChEBI ID CHEBI:83687
Definition A racemate comprising equimolar amounts of (R)- and (S)-sertaconazole nitrate. A broad spectrum antifungal with added antipruritic and anti-inflammatory activity used for treatment of various skin infections.
Stars This entity has been manually annotated by the ChEBI Team.
Formula C20H16Cl3N3O4S
Net Charge 0
Average Mass 500.78300
Monoisotopic Mass 498.99271
Roles Classification
Biological Role(s): EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14alpha-demethylase).
antibacterial drug
A drug used to treat or prevent bacterial infections.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via imidazole antifungal drug )
(via conazole antifungal drug )
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via imidazole antifungal agent )
(via conazole antifungal agent )
ergosterol biosynthesis inhibitor
Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol.
(via conazole antifungal agent )
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
antipruritic drug
A drug, usually applied topically, that relieves pruritus (itching).
antibacterial drug
A drug used to treat or prevent bacterial infections.
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via imidazole antifungal drug )
(via conazole antifungal drug )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing sertaconazole nitrate (CHEBI:83687) has part (S)-sertaconazole nitrate (CHEBI:83691)
sertaconazole nitrate (CHEBI:83687) has part arasertaconazole nitrate (CHEBI:83692)
sertaconazole nitrate (CHEBI:83687) has role antibacterial drug (CHEBI:36047)
sertaconazole nitrate (CHEBI:83687) has role antipruritic drug (CHEBI:59683)
sertaconazole nitrate (CHEBI:83687) has role EC 1.14.13.70 (sterol 14α-demethylase) inhibitor (CHEBI:77884)
sertaconazole nitrate (CHEBI:83687) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
sertaconazole nitrate (CHEBI:83687) is a conazole antifungal drug (CHEBI:87071)
sertaconazole nitrate (CHEBI:83687) is a imidazole antifungal drug (CHEBI:87069)
sertaconazole nitrate (CHEBI:83687) is a racemate (CHEBI:60911)
IUPAC Name
rac-1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate
Synonyms Sources
(±)-sertaconazole nitrate ChEBI
(RS)-sertaconazole nitrate ChEBI
rac-sertaconazole nitrate ChEBI
racemic sertaconazole nitrate ChEBI
sertaconazole mononitrate ChEBI
Brand Names Sources
Ertaczo KEGG DRUG
Zalain KEGG DRUG
Manual Xrefs Databases
D08510 KEGG DRUG
DB01153 DrugBank
MX2007002924 Patent
View more database links
Registry Numbers Types Sources
5375607 Reaxys Registry Number Reaxys
99592-39-9 CAS Registry Number ChemIDplus
99592-39-9 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
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Last Modified
23 July 2015