CHEBI:6649 - malaoxon

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ChEBI Name malaoxon
ChEBI ID CHEBI:6649
Definition A racemate comprising equimolar amounts of (R) and (S)-malaoxon. It is the active insecticide of the proinsecticide malathion.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): EC 3.1.1.7 (acetylcholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
EC 3.1.1.8 (cholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
Application(s): agrochemical
An agrochemical is a substance that is used in agriculture or horticulture.
pediculicide
Substance used to treat lice (genus Pediculus) infestation.
scabicide
An acaricide that kills mites of the genus Sarcoptes.
insecticide
Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
(via organophosphorus insecticide )
pesticide
Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
(via organophosphorus pesticide )
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ChEBI Ontology
Outgoing malaoxon (CHEBI:6649) has part (R)-malaoxon (CHEBI:141478)
malaoxon (CHEBI:6649) has part (S)-malaoxon (CHEBI:141479)
malaoxon (CHEBI:6649) has role agrochemical (CHEBI:33286)
malaoxon (CHEBI:6649) has role EC 3.1.1.7 (acetylcholinesterase) inhibitor (CHEBI:38462)
malaoxon (CHEBI:6649) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733)
malaoxon (CHEBI:6649) has role insecticide (CHEBI:24852)
malaoxon (CHEBI:6649) has role pediculicide (CHEBI:38706)
malaoxon (CHEBI:6649) has role scabicide (CHEBI:73333)
malaoxon (CHEBI:6649) is a organothiophosphate insecticide (CHEBI:25715)
malaoxon (CHEBI:6649) is a racemate (CHEBI:60911)
IUPAC Name
rac-diethyl 2-[(dimethoxyphosphoryl)thio]succinate
Synonyms Sources
diethyl 2-dimethoxyphosphorylsulfanylbutanedioate ChEBI
dimethoxyphosphorylsulfanyl-succinic acid diethyl ester ChEBI
Liromat ChEBI
O,O-Dimethyl S-(1,2-dicarbethoxy)ethyl phosphorothioate ChEBI
oxycarbophos ChEBI
rac-malaoxon ChEBI
Manual Xref Database
Malaoxon Wikipedia
View more database links
Registry Numbers Types Sources
1634-78-2 CAS Registry Number ChemIDplus
1634-78-2 CAS Registry Number NIST Chemistry WebBook
1804523 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
26173615 PubMed citation Europe PMC
28849997 PubMed citation Europe PMC
7894269 PubMed citation Europe PMC
8292751 PubMed citation Europe PMC
8292752 PubMed citation Europe PMC
Last Modified
10 May 2019