CHEBI:31633 - formoterol fumarate

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ChEBI Name formoterol fumarate ChEBI ID CHEBI:31633 Definition A racemate consisting of equal amounts of arformoterol fumarate (the active enantiomer) and (S,S)-formoterol fumarate (the inactive enantiomer). It is used (particularly in its dihydrate form) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema). Stars This entity has been manually annotated by the ChEBI Team. Formulae 2C19H24N2O4.C4H4O4 C42H52N4O12 Net Charge 0 Average Mass 804.88190 Monoisotopic Mass 804.35817 Roles Classification Biological Role(s): beta-adrenergic agonist An agent that selectively binds to and activates beta-adrenergic receptors. Application(s): anti-asthmatic drug A drug used to treat asthma. beta-adrenergic agonist An agent that selectively binds to and activates beta-adrenergic receptors. bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. View more via ChEBI Ontology ChEBI Ontology Outgoing formoterol fumarate (CHEBI:31633) has part (S,S)-formoterol fumarate (CHEBI:63109) formoterol fumarate (CHEBI:31633) has part arformoterol fumarate (CHEBI:63108) formoterol fumarate (CHEBI:31633) has part formoterol(1+) (CHEBI:63111) formoterol fumarate (CHEBI:31633) has role β-adrenergic agonist (CHEBI:35522) formoterol fumarate (CHEBI:31633) has role anti-asthmatic drug (CHEBI:49167) formoterol fumarate (CHEBI:31633) has role bronchodilator agent (CHEBI:35523) formoterol fumarate (CHEBI:31633) is a racemate (CHEBI:60911) Incoming Bevespi Aerosphere (CHEBI:133025) has part formoterol fumarate (CHEBI:31633) IUPAC Name rac-bis[(2R)-N-{(2R)-2-[3-(formylamino)-4-hydroxyphenyl]-2-hydroxyethyl}-1-(4-methoxyphenyl)propan-2-aminium] (2E)-but-2-enedioate Synonyms Sources formoterol hemifumarate ChEBI rac-N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide (2E)-but-2-enedioate IUPAC Manual Xrefs Databases D01373 KEGG DRUG DB00983 DrugBank View more database links Registry Numbers Types Sources 43229-80-7 CAS Registry Number ChemIDplus 43229-80-7 CAS Registry Number KEGG DRUG 8463050 Reaxys Registry Number Reaxys Citations Types Sources 18655841 PubMed citation Europe PMC 20477569 PubMed citation Europe PMC Last Modified 09 September 2016