zarzissine (CHEBI:66501)

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ChEBI Name	zarzissine

ChEBI ID	CHEBI:66501

Definition	A organonitrogen heterocyclic compound that is 1H-imidazo[4,5-d]pyridazine substituted by an amino group at position 2. A guanidine alkaloid isolated from Anchinoe paupertas, it exhibits cytotoxic activity against human and murine tumor cell lines.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C5H5N5

Net Charge

Average Mass

135.12670

Monoisotopic Mass

135.05450

InChI

InChI=1S/C5H5N5/c6-5-9-3-1-7-8-2-4(3)10-5/h1-2H,(H3,6,9,10)

InChIKey

BUYBPEINWQQOFV-UHFFFAOYSA-N

SMILES

Nc1nc2cnncc2[nH]1

Metabolite of Species	Details
Anchinoe paupertas (WORMS:234358)	See: PubMed

Roles Classification
Biological Role(s):	metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. (via alkaloid )

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	zarzissine (CHEBI:66501) has role antineoplastic agent (CHEBI:35610) zarzissine (CHEBI:66501) has role metabolite (CHEBI:25212) zarzissine (CHEBI:66501) is a alkaloid (CHEBI:22315) zarzissine (CHEBI:66501) is a guanidines (CHEBI:24436) zarzissine (CHEBI:66501) is a organonitrogen heterocyclic compound (CHEBI:38101)

IUPAC Name

1H-imidazo[4,5-d]pyridazin-2-amine

Last Modified

12 July 2013