Services
Research
Training
Industry
About us
ChEBI
Examples:
iron*
,
InChI=1S/CH4O/c1-2/h2H,1H3
,
caffeine
Advanced
Home
Advanced Search
Browse
Documentation
Download
Tools
About ChEBI
Submit
Contact us
DiNA
Statistics
Entity of the Month
Periodic Table
Ontology
Train online
User Manual
Annotation Manual
Developer Manual
FAQ's
BiNChE
libChEBI
Web Services
ChEBI
> Main
CHEBI:8024 - perindopril
Main
ChEBI Ontology
Automatic Xrefs
Reactions
Pathways
Models
ChEBI Name
perindopril
ChEBI ID
CHEBI:8024
Definition
An α-amino acid ester that is the ethyl ester of
N
-{(2
S
)-1-[(2
S
,3a
S
,7a
S
)-2-carboxyoctahydro-1
H
-indol-1-yl]-1-oxopropan-2-yl}-
L
-norvaline
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download
Molfile
XML
SDF
Find compounds which contain this structure
Find compounds which resemble this structure
Take structure to the Advanced Search
Wikipedia
License
Read full article at Wikipedia
Formula
C19H32N2O5
Net Charge
0
Average Mass
368.46786
Monoisotopic Mass
368.23112
InChI
InChI=1S/C19H32N2O5/c1-
4-
8-
14(19(25)
26-
5-
2)
20-
12(3)
17(22)
21-
15-
10-
7-
6-
9-
13(15)
11-
16(21)
18(23)
24/h12-
16,20H,4-
11H2,1-
3H3,(H,23,24)
/t12-
,13-
,14-
,15-
,16-
/m0/s1
InChIKey
IPVQLZZIHOAWMC-QXKUPLGCSA-N
SMILES
[H][C@@]12CCCC[C@]1([H])N([C@@H](C2)C(O)=O)C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC
Roles Classification
Chemical Role
(s):
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Br
o
nsted base).
(via
oxoacid
)
Biological Role
(s):
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
Application
(s):
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
perindopril (
CHEBI:8024
)
has role
antihypertensive agent (
CHEBI:35674
)
perindopril (
CHEBI:8024
)
has role
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor (
CHEBI:35457
)
perindopril (
CHEBI:8024
)
is a
α-amino acid ester (
CHEBI:46874
)
perindopril (
CHEBI:8024
)
is a
dicarboxylic acid monoester (
CHEBI:36244
)
perindopril (
CHEBI:8024
)
is a
ethyl ester (
CHEBI:23990
)
perindopril (
CHEBI:8024
)
is a
organic heterobicyclic compound (
CHEBI:27171
)
perindopril (
CHEBI:8024
)
is conjugate acid of
perindopril(1−) (
CHEBI:78000
)
Incoming
perindopril(1−) (
CHEBI:78000
)
is conjugate base of
perindopril (
CHEBI:8024
)
IUPAC Name
ethyl
N
-
{(2
S
)-
1-
[(2
S
,3a
S
,7a
S
)-
2-
carboxyoctahydro-
1
H
-
indol-
1-
yl]-
1-
oxopropan-
2-
yl}-
L
-
norvalinate
INNs
Sources
perindopril
ChemIDplus
perindoprilum
ChemIDplus
Synonym
Source
(2
S
,3a
S
,7a
S
)-
1-
[(2
S
)-
2-
{[(2
S
)-
1-
ethoxy-
1-
oxopentan-
2-
yl]amino}propanoyl]octahydro-
1
H
-
indole-
2-
carboxylic acid
IUPAC
Manual Xrefs
Databases
2108
DrugCentral
C07706
KEGG COMPOUND
D03753
KEGG DRUG
DB00790
DrugBank
HMDB0014928
HMDB
LSM-4080
LINCS
Perindopril
Wikipedia
View more database links
Registry Numbers
Types
Sources
4300272
Reaxys Registry Number
Reaxys
82834-16-0
CAS Registry Number
ChemIDplus
Citations
Types
Sources
24291100
PubMed citation
Europe PMC
24324048
PubMed citation
Europe PMC
24357222
PubMed citation
Europe PMC
24511479
PubMed citation
Europe PMC
24515310
PubMed citation
Europe PMC
24554346
PubMed citation
Europe PMC
24590580
PubMed citation
Europe PMC
24602481
PubMed citation
Europe PMC
24664905
PubMed citation
Europe PMC
Last Modified
22 February 2017