CHEBI:50214 - pizotifen maleate

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ChEBI Name pizotifen maleate
ChEBI ID CHEBI:50214
Definition A maleate salt obtained by reaction of pizotifen with one equivalent of maleic acid.
Stars This entity has been manually annotated by the ChEBI Team.
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Formulae C19H21NS.C4H4O4
C23H25NO4S
Net Charge 0
Average Mass 411.51400
Monoisotopic Mass 411.15043
InChI InChI=1S/C19H21NS.C4H4O4/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18;5-3(6)1-2-4(7)8/h2-5,10,13H,6-9,11-12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKey GGYSHFFKUHGBIK-BTJKTKAUSA-N
SMILES OC(=O)\C=C/C(O)=O.CN1CCC(CC1)=C1c2ccccc2CCc2sccc12
Roles Classification
Biological Role(s): histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Application(s): histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
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ChEBI Ontology
Outgoing pizotifen maleate (CHEBI:50214) has part pizotifen(1+) (CHEBI:50318)
pizotifen maleate (CHEBI:50214) has role histamine antagonist (CHEBI:37956)
pizotifen maleate (CHEBI:50214) has role muscarinic antagonist (CHEBI:48876)
pizotifen maleate (CHEBI:50214) has role serotonergic antagonist (CHEBI:48279)
pizotifen maleate (CHEBI:50214) is a maleate salt (CHEBI:50221)
IUPAC Name
4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine (2Z)but-2-enedioate
Synonyms Sources
4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine maleate ChEBI
4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidinium (2Z)-3-carboxybut-2-enoate IUPAC
4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidinium hydrogen maleate ChEBI
pizotifen hydrogen maleate ChEBI
Registry Numbers Types Sources
24359-22-6 CAS Registry Number ChemIDplus
5720406 Reaxys Registry Number Reaxys
5720406 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
3394590 PubMed citation Europe PMC
6420809 PubMed citation Europe PMC
6431474 PubMed citation Europe PMC
Last Modified
16 April 2012