CHEBI:3252 - C-1027 chromophore

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ChEBI Name C-1027 chromophore
ChEBI ID CHEBI:3252
Definition An enediyne antibiotic that has formula C43H42ClN3O13. It is a natural product found in Streptomyces globisporus and exhibits antimicrobial and antineoplastic properties.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:68320
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Formula C43H42ClN3O13
Net Charge 0
Average Mass 844.270
Monoisotopic Mass 843.24062
InChI InChI=1S/C43H42ClN3O13/c1-21-39(52)46-34-26(17-25(54-6)18-30(34)56-21)40(53)57-31-20-55-33(49)19-28(45)23-15-27(44)37(29(48)16-23)58-32-11-7-9-22(31)12-13-24-10-8-14-43(24,32)60-41-36(51)35(50)38(47(4)5)42(2,3)59-41/h8-10,14-18,28,31-32,35-36,38,41,48,50-51H,1,19-20,45H2,2-6H3,(H,46,52)/b22-9+/t28-,31-,32+,35-,36+,38-,41-,43+/m0/s1
InChIKey DGGZCXUXASNDAC-QQNGCVSVSA-N
SMILES [H][C@@]1(O[C@]23C=CC=C2C#CC2=CC#C[C@@]3([H])OC3=C(Cl)C=C(C=C3O)[C@@H](N)CC(=O)OC[C@@H]2OC(=O)C2=CC(OC)=CC3=C2NC(=O)C(=C)O3)OC(C)(C)[C@H]([C@@H](O)[C@H]1O)N(C)C
Metabolite of Species Details
Streptomyces globisporus C-1027 (NCBI:txid1172567) See: PubMed
Streptomyces sp. CB02366 (NCBI:txid1703935) See: PubMed
Streptomyces sp. CB00657 (NCBI:txid1718958) See: PubMed
Streptomyces sp. CB02329 (NCBI:txid171897) See: PubMed
Streptomyces sp. CB03608 (NCBI:txid1718988) See: PubMed
Streptomyces globisporus (NCBI:txid1908) See: PubMed
Streptomyces globisporus (NCBI:txid1908) of strain SB 1021 See: PubMed
Streptomyces globisporus (NCBI:txid1908) of strain SB 1023 See: PubMed
Streptomyces globisporus (NCBI:txid1908) of strain SB 1014 See: PubMed
Streptomyces globisporus (NCBI:txid1908) of strain SB 1022 See: PubMed
Roles Classification
Biological Role(s): bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via carbocyclic antibiotic )
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing C-1027 chromophore (CHEBI:3252) has role antimicrobial agent (CHEBI:33281)
C-1027 chromophore (CHEBI:3252) has role antineoplastic agent (CHEBI:35610)
C-1027 chromophore (CHEBI:3252) has role apoptosis inducer (CHEBI:68495)
C-1027 chromophore (CHEBI:3252) has role bacterial metabolite (CHEBI:76969)
C-1027 chromophore (CHEBI:3252) is a amino sugar (CHEBI:28963)
C-1027 chromophore (CHEBI:3252) is a aromatic ether (CHEBI:35618)
C-1027 chromophore (CHEBI:3252) is a benzoxazine (CHEBI:46969)
C-1027 chromophore (CHEBI:3252) is a diester (CHEBI:51307)
C-1027 chromophore (CHEBI:3252) is a enediyne antibiotic (CHEBI:53268)
C-1027 chromophore (CHEBI:3252) is a monochlorobenzenes (CHEBI:83403)
C-1027 chromophore (CHEBI:3252) is a phenols (CHEBI:33853)
IUPAC Name
[1R,7S,12R,13(23)E,20R]-7-amino-4-chloro-20-{[(2S,3R,4R,5S)-5-(dimethylamino)-3,4-dihydroxy-6,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-25-hydroxy-9-oxo-2,10-dioxatetracyclo[11.7.3.23,6.016,20]pentacosa-3,5,13(23),16,18,24-hexaene-14,21-diyn-12-yl 7-methoxy-2-methylidene-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-5-carboxylate
Synonyms Sources
antibiotic C-1027 ChemIDplus
C 1027 ChemIDplus
C-1027 KEGG COMPOUND
C-1027 chromophore KEGG COMPOUND
C1027 chromophore ChemIDplus
C1027 chromoprotein ChemIDplus
lidamycin ChemIDplus
Manual Xrefs Databases
8138248 ChemSpider
C-1027 Wikipedia
C11438 KEGG COMPOUND
US7109019 Patent
View more database links
Registry Number Type Source
120177-69-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
12 January 2022