CHEBI:3438 - carteolol hydrochloride

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ChEBI Name carteolol hydrochloride
ChEBI ID CHEBI:3438
Stars This entity has been manually annotated by the ChEBI Team.
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Formulae C16H24N2O3.HCl
C16H25ClN2O3
Net Charge 0
Average Mass 328.83400
Monoisotopic Mass 328.15537
InChI InChI=1S/C16H24N2O3.ClH/c1-16(2,3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13;/h4-6,11,17,19H,7-10H2,1-3H3,(H,18,20);1H
InChIKey FYBXRCFPOTXTJF-UHFFFAOYSA-N
SMILES [Cl-].CC(C)(C)[NH2+]CC(O)COc1cccc2NC(=O)CCc12
Roles Classification
Biological Role(s): beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
Application(s): antiglaucoma drug
Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
anti-arrhythmia drug
A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
beta-adrenergic antagonist
An agent that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of endogenous or exogenous beta-adrenergic agonists. beta-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
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ChEBI Ontology
Outgoing carteolol hydrochloride (CHEBI:3438) has part carteolol(1+) (CHEBI:61202)
carteolol hydrochloride (CHEBI:3438) has role β-adrenergic antagonist (CHEBI:35530)
carteolol hydrochloride (CHEBI:3438) has role anti-arrhythmia drug (CHEBI:38070)
carteolol hydrochloride (CHEBI:3438) has role antiglaucoma drug (CHEBI:39456)
carteolol hydrochloride (CHEBI:3438) has role antihypertensive agent (CHEBI:35674)
carteolol hydrochloride (CHEBI:3438) is a hydrochloride (CHEBI:36807)
IUPAC Name
5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydroquinolin-2(1H)-one hydrochloride
Synonyms Sources
5-(2-Hydroxy-3-tert-butylamino)propoxy-3,4-dihydrocarbostyril hydrochloride ChemIDplus
5-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-2(1H)-quinolinone hydrochloride ChemIDplus
5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydrocarbostyril monohydrochloride ChemIDplus
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-2(1H)-chinolinon-hydrochlorid ChemIDplus
Carteolol HCl ChemIDplus
N-tert-butyl-2-hydroxy-3-[(2-oxo-1,2,3,4-tetrahydroquinolin-5-yl)oxy]propan-1-aminium chloride IUPAC
Manual Xrefs Databases
D00599 KEGG DRUG
DB00521 DrugBank
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Registry Numbers Types Sources
51781-21-6 CAS Registry Number ChemIDplus
5784965 Beilstein Registry Number Beilstein
Last Modified
03 February 2011