CHEBI:74957 - 4',6,7-trihydroxyisoflavone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 4',6,7-trihydroxyisoflavone
Definition A hydroxyisoflavone that is daidzein bearing an additional hydroxy substituent at position 6.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Anonymous
Secondary ChEBI IDs CHEBI:34358
Supplier Information
Download Molfile XML SDF
Formula C15H10O5
Net Charge 0
Average Mass 270.23690
Monoisotopic Mass 270.05282
InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-14-6-13(18)12(17)5-10(14)15(11)19/h1-7,16-18H
SMILES Oc1ccc(cc1)-c1coc2cc(O)c(O)cc2c1=O
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
PPARalpha agonist
A PPAR modulator which activates the peroxisome proliferator-activated receptor-alpha.
PPARgamma agonist
A PPAR modulator which activates the peroxisome proliferator-activated receptor-gamma.
An agent that reduces or interferes with the mutagenic actions or effects of a substance.
EC (tyrosinase) inhibitor
Any EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosinase (monophenol monooxygenase), EC, an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals.
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
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ChEBI Ontology
Outgoing 4',6,7-trihydroxyisoflavone (CHEBI:74957) has functional parent daidzein (CHEBI:28197)
4',6,7-trihydroxyisoflavone (CHEBI:74957) has role anti-inflammatory agent (CHEBI:67079)
4',6,7-trihydroxyisoflavone (CHEBI:74957) has role antimutagen (CHEBI:73190)
4',6,7-trihydroxyisoflavone (CHEBI:74957) has role EC (tyrosinase) inhibitor (CHEBI:59997)
4',6,7-trihydroxyisoflavone (CHEBI:74957) has role metabolite (CHEBI:25212)
4',6,7-trihydroxyisoflavone (CHEBI:74957) has role PPARα agonist (CHEBI:70782)
4',6,7-trihydroxyisoflavone (CHEBI:74957) has role PPARγ agonist (CHEBI:71554)
4',6,7-trihydroxyisoflavone (CHEBI:74957) is a 7-hydroxyisoflavones (CHEBI:55465)
Synonyms Sources
6,7,4'-trihydroxyisoflavone MetaCyc
6-Hydroxydaidzein HMDB
6-Hydroxydaidzein KEGG COMPOUND
Manual Xrefs Databases
C00009385 KNApSAcK
CPD-6998 MetaCyc
HMDB0031715 HMDB
View more database links
Registry Numbers Types Sources
1291621 Reaxys Registry Number Reaxys
17817-31-1 CAS Registry Number KEGG COMPOUND
17817-31-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10540753 PubMed citation Europe PMC
12784638 PubMed citation Europe PMC
15215607 PubMed citation Europe PMC
15914921 PubMed citation Europe PMC
16372328 PubMed citation Europe PMC
18724264 PubMed citation Europe PMC
20142789 PubMed citation Europe PMC
Last Modified
28 July 2014