CHEBI:85196 - peramivir hydrate

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ChEBI Name peramivir hydrate
ChEBI ID CHEBI:85196
Definition A hydrate that is the trihydrate form of peramivir. Used for the treatment of acute uncomplicated influenza in patients 18 years and older who have been symptomatic for no more than two days.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C15H36N4O8
Net Charge 0
Average Mass 400.46830
Monoisotopic Mass 400.25331
InChI InChI=1S/C15H28N4O4.4H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);4*1H2/t9-,10+,11+,12-,13+;;;;/m0..../s1
InChIKey UGTYTOKVOXBJBZ-LINPMSLLSA-N
SMILES O.O.O.O.CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@H](C[C@H]1NC(N)=N)C(O)=O
Roles Classification
Biological Role(s): EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Application(s): EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
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ChEBI Ontology
Outgoing peramivir hydrate (CHEBI:85196) has role antiviral drug (CHEBI:36044)
peramivir hydrate (CHEBI:85196) has role EC 3.2.1.18 (exo-α-sialidase) inhibitor (CHEBI:52425)
peramivir hydrate (CHEBI:85196) is a hydrate (CHEBI:35505)
Incoming peramivir (CHEBI:85202) has part peramivir hydrate (CHEBI:85196)
IUPAC Name
(1S,2S,3R,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-carbamimidamido-2-hydroxycyclopentane-1-carboxylic acid—water (1/3)
INN Source
peramivir KEGG DRUG
Synonym Source
Peramivir trihydrate ChemIDplus
Brand Name Source
RAPIVAB KEGG DRUG
Manual Xrefs Databases
D03829 KEGG DRUG
Peramivir Wikipedia
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Registry Numbers Types Sources
1041434-82-5 CAS Registry Number ChemIDplus
18582192 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
24517996 PubMed citation Europe PMC
25231091 PubMed citation Europe PMC
25277670 PubMed citation Europe PMC
25523716 PubMed citation Europe PMC
25547357 PubMed citation Europe PMC
25691635 PubMed citation Europe PMC
25697190 PubMed citation Europe PMC
25752738 PubMed citation Europe PMC
Last Modified
07 January 2016