CHEBI:31483 - diflorasone diacetate

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name diflorasone diacetate
ChEBI ID CHEBI:31483
Definition The 17,21-diacetate derivative of diflorasone. It is used topically for its anti-inflammatory and antipruritic properties in the treatment of various skin disorders.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C26H32F2O7
Net Charge 0
Average Mass 494.52490
Monoisotopic Mass 494.21161
InChI InChI=1S/C26H32F2O7/c1-13-8-17-18-10-20(27)19-9-16(31)6-7-23(19,4)25(18,28)21(32)11-24(17,5)26(13,35-15(3)30)22(33)12-34-14(2)29/h6-7,9,13,17-18,20-21,32H,8,10-12H2,1-5H3/t13-,17-,18-,20-,21-,23-,24-,25-,26-/m0/s1
InChIKey BOBLHFUVNSFZPJ-JOYXJVLSSA-N
SMILES [H][C@@]12C[C@H](C)[C@](OC(C)=O)(C(=O)COC(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
Roles Classification
Biological Role(s): hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
Application(s): anti-inflammatory drug
A substance that reduces or suppresses inflammation.
antipruritic drug
A drug, usually applied topically, that relieves pruritus (itching).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing diflorasone diacetate (CHEBI:31483) has functional parent acetic acid (CHEBI:15366)
diflorasone diacetate (CHEBI:31483) has functional parent diflorasone (CHEBI:59750)
diflorasone diacetate (CHEBI:31483) has parent hydride pregnane (CHEBI:8386)
diflorasone diacetate (CHEBI:31483) has role anti-inflammatory drug (CHEBI:35472)
diflorasone diacetate (CHEBI:31483) has role antipruritic drug (CHEBI:59683)
diflorasone diacetate (CHEBI:31483) is a 11β-hydroxy steroid (CHEBI:35346)
diflorasone diacetate (CHEBI:31483) is a 20-oxo steroid (CHEBI:36885)
diflorasone diacetate (CHEBI:31483) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166)
diflorasone diacetate (CHEBI:31483) is a acetate ester (CHEBI:47622)
diflorasone diacetate (CHEBI:31483) is a fluorinated steroid (CHEBI:50830)
diflorasone diacetate (CHEBI:31483) is a glucocorticoid (CHEBI:24261)
IUPAC Name
6α,9-difluoro-11β-hydroxy-16β-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl diacetate
Synonyms Sources
(6α,11β,16β)-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl diacetate ChEBI
6α,9-difluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-diacetate ChemIDplus
diflorasone 17,21-diacetate ChEBI
diflorasone di(acetate) ChemIDplus
Manual Xrefs Databases
4485 DrugCentral
D01327 KEGG DRUG
DB00223 DrugBank
DE2308731 Patent
US3980778 Patent
View more database links
Registry Numbers Types Sources
33564-31-7 CAS Registry Number ChemIDplus
33564-31-7 CAS Registry Number KEGG DRUG
8175887 Beilstein Registry Number Beilstein
Last Modified
22 February 2017