sulfadoxine (CHEBI:9329)

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ChEBI Name	sulfadoxine

ChEBI ID	CHEBI:9329

Definition	A sulfonamide consisting of pyrimidine having methoxy substituents at the 5- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. In combination with the antiprotozoal pyrimethamine (CHEBI:8673) it is used as an antimalarial.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C12H14N4O4S

Net Charge

Average Mass

310.33012

Monoisotopic Mass

310.07358

InChI

InChI=1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)

InChIKey

PJSFRIWCGOHTNF-UHFFFAOYSA-N

SMILES

COc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC

Roles Classification
Biological Role(s):	antibacterial drug A drug used to treat or prevent bacterial infections. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.

Application(s):	antibacterial drug A drug used to treat or prevent bacterial infections. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.

ChEBI Ontology
Outgoing	sulfadoxine (CHEBI:9329) has role antibacterial drug (CHEBI:36047) sulfadoxine (CHEBI:9329) has role antimalarial (CHEBI:38068) sulfadoxine (CHEBI:9329) is a pyrimidines (CHEBI:39447) sulfadoxine (CHEBI:9329) is a sulfonamide (CHEBI:35358)

IUPAC Name

4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide

Synonyms	Sources
4-Sulfanilamido-5,6-dimethoxypyrimidine	ChemIDplus
Sulfadoxine	KEGG COMPOUND
Sulforthomidine	ChemIDplus
Sulphadoxine	ChemIDplus
Sulphormethoxine	ChemIDplus

Last Modified

22 February 2017