7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid (CHEBI:68708)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid

ChEBI ID	CHEBI:68708

ChEBI ASCII Name	7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid

Definition	A pyridochromene that is 10H-chromeno[3,2-c]pyridine substituted by hydroxy groups at positions 7 and 8, a methyl group at position 3, an oxo group at position 10 and a carboxy group at position 9. Isolated from Chaetomium funicola, it exhibits inhibitory activity against metallo-β-lactamases.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C14H9NO6

Net Charge

Average Mass

287.22440

Monoisotopic Mass

287.04299

InChI

InChI=1S/C14H9NO6/c1-5-2-8-6(4-15-5)12(17)10-9(21-8)3-7(16)13(18)11(10)14(19)20/h2-4,16,18H,1H3,(H,19,20)

InChIKey

JQSDDXAUCUZICT-UHFFFAOYSA-N

SMILES

Cc1cc2oc3cc(O)c(O)c(C(O)=O)c3c(=O)c2cn1

Metabolite of Species	Details
Chaetomium funicola (NCBI:txid79816)	See: PubMed

Roles Classification
Chemical Role(s):	Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid )

Biological Role(s):	Chaetomium metabolite Any fungal metabolite produced during a metabolic reaction in the mould, Chaetomium. EC 3.5.2.6 (beta-lactamase) inhibitor An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6).

ChEBI Ontology
Outgoing	7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid (CHEBI:68708) has role Chaetomium metabolite (CHEBI:76960) 7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid (CHEBI:68708) has role EC 3.5.2.6 (β-lactamase) inhibitor (CHEBI:35625) 7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid (CHEBI:68708) is a catechols (CHEBI:33566) 7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid (CHEBI:68708) is a cyclic ketone (CHEBI:3992) 7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid (CHEBI:68708) is a monocarboxylic acid (CHEBI:25384) 7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid (CHEBI:68708) is a pyridochromene (CHEBI:53792)

IUPAC Name

7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid

Synonym	Source
SB236049	ChEBI

Registry Number	Type	Source
9576391	Reaxys Registry Number	Reaxys

Citation	Type	Source
12019104	PubMed citation	Europe PMC

Last Modified

13 January 2014