CHEBI:65991 - guttiferone F

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ChEBI Name guttiferone F
ChEBI ID CHEBI:65991
Definition A member of the class of benzophenones isolated from the stem bark of Allanblackia stuhlmannii and has been shown to exhibit antileishmanial and anticholinesterase activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C38H50O6
Net Charge 0
Average Mass 602.80000
Monoisotopic Mass 602.36074
InChI InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-40,42H,7,13,15,18,20-21H2,1-6,8-10H3/t27-,28-,37-,38+/m1/s1
InChIKey QDKLRKZQSOQWJQ-LPEHXNHASA-N
SMILES CC(C)=CC[C@H](C[C@@]12C[C@@H](CC=C(C)C)C(C)(C)[C@@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)=C1O)C2=O)C(C)=C
Metabolite of Species Details
Allanblackia stuhlmannii (IPNI:427050-1) Found in xylem (BTO:0001468). Previous component: root wood; See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
EC 3.1.1.8 (cholinesterase) inhibitor
An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
Application(s): antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing guttiferone F (CHEBI:65991) has role antileishmanial agent (CHEBI:70868)
guttiferone F (CHEBI:65991) has role apoptosis inducer (CHEBI:68495)
guttiferone F (CHEBI:65991) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733)
guttiferone F (CHEBI:65991) has role metabolite (CHEBI:25212)
guttiferone F (CHEBI:65991) is a benzophenones (CHEBI:22726)
guttiferone F (CHEBI:65991) is a bridged compound (CHEBI:35990)
guttiferone F (CHEBI:65991) is a polyphenol (CHEBI:26195)
IUPAC Name
(1R,5R,7R)-3-(3,4-dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methylbut-2-en-1-yl)-5-[(2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]bicyclo[3.3.1]non-3-ene-2,9-dione
Manual Xref Database
10282668 ChemSpider
View more database links
Registry Number Type Source
4731414 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
17960072 PubMed citation Europe PMC
18322848 PubMed citation Europe PMC
20681570 PubMed citation Europe PMC
9917299 PubMed citation Europe PMC
Last Modified
18 February 2013