CHEBI:66066 - IC202B

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ChEBI Name IC202B
ChEBI ID CHEBI:66066
Definition A C-nitro compound isolated from Streptoalloteichus sp.1454-19. It is a siderophore which exhibits immunosuppressive activity on a mixed lymphocyte culture reaction (MLCR).
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C23H44N6O8
Net Charge 0
Average Mass 532.63090
Monoisotopic Mass 532.32206
InChI InChI=1S/C23H44N6O8/c24-14-4-1-7-17-27(34)22(32)12-10-20(30)25-15-5-2-8-18-28(35)23(33)13-11-21(31)26-16-6-3-9-19-29(36)37/h34-35H,1-19,24H2,(H,25,30)(H,26,31)
InChIKey BHNYEXHOBOECJW-UHFFFAOYSA-N
SMILES NCCCCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(=O)CCC(=O)NCCCCC[N+]([O-])=O
Metabolite of Species Details
Streptoalloteichus (NCBI:txid44103) of strain 1454-19 See: PubMed
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
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ChEBI Ontology
Outgoing IC202B (CHEBI:66066) has role antimicrobial agent (CHEBI:33281)
IC202B (CHEBI:66066) has role immunosuppressive agent (CHEBI:35705)
IC202B (CHEBI:66066) has role metabolite (CHEBI:25212)
IC202B (CHEBI:66066) is a C-nitro compound (CHEBI:35716)
IC202B (CHEBI:66066) is a hydroxamic acid (CHEBI:24650)
IC202B (CHEBI:66066) is a primary amino compound (CHEBI:50994)
IUPAC Name
N-(5-aminopentyl)-N-hydroxy-N'-[5-(hydroxy{4-[(5-nitropentyl)amino]-4-oxobutanoyl}amino)pentyl]butanediamide
Registry Number Type Source
8462473 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
10726924 PubMed citation Europe PMC
Last Modified
02 November 2012