CHEBI:31353 - carbinoxamine maleate

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ChEBI Name carbinoxamine maleate
ChEBI ID CHEBI:31353
Definition The maleic acid salt of carbinoxamine. An ethanolamine-type antihistamine, used for treating hay fever, as well as mild cases of Parkinson's disease.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C20H23ClN2O5
Net Charge 0
Average Mass 406.86000
Monoisotopic Mass 406.12955
InChI InChI=1S/C16H19ClN2O.C4H4O4/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-10,16H,11-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKey GVNWHCVWDRNXAZ-BTJKTKAUSA-N
SMILES OC(=O)\C=C/C(O)=O.CN(C)CCOC(c1ccc(Cl)cc1)c1ccccn1
Roles Classification
Biological Role(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Application(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
anti-allergic agent
A drug used to treat allergic reactions.
muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antiparkinson drug
A drug used in the treatment of Parkinson's disease.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing carbinoxamine maleate (CHEBI:31353) has part carbinoxamine (CHEBI:3398)
carbinoxamine maleate (CHEBI:31353) has role anti-allergic agent (CHEBI:50857)
carbinoxamine maleate (CHEBI:31353) has role antiparkinson drug (CHEBI:48407)
carbinoxamine maleate (CHEBI:31353) has role H1-receptor antagonist (CHEBI:37955)
carbinoxamine maleate (CHEBI:31353) has role muscarinic antagonist (CHEBI:48876)
carbinoxamine maleate (CHEBI:31353) is a maleate salt (CHEBI:50221)
Incoming (S)-carbinoxamine maleate (CHEBI:59330) is a carbinoxamine maleate (CHEBI:31353)
IUPAC Name
2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]-N,N-dimethylethanamine (2Z)-but-2-enedioate
Synonyms Sources
2-(p-chloro-α-(2-(dimethylamino)ethoxy)benzyl)pyridine maleate ChemIDplus
2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]-N,N-dimethylethanamine maleate ChEBI
p-carbinoxamine maleate ChemIDplus
paracarbinoxamine maleate ChEBI
Manual Xrefs Databases
D01336 KEGG DRUG
DB00748 DrugBank
View more database links
Registry Numbers Types Sources
3505-38-2 CAS Registry Number ChemIDplus
3505-38-2 CAS Registry Number KEGG DRUG
6557352 Beilstein Registry Number Beilstein
Last Modified
30 April 2010