CHEBI:59169 - benzphetamine hydrochloride

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ChEBI Name benzphetamine hydrochloride
ChEBI ID CHEBI:59169
Definition The hydrochloride salt of benzphetamine. A sympathomimetic agent with properties similar to dextroamphetamine, it is used in the treatment of obesity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C17H22ClN
Net Charge 0
Average Mass 275.81600
Monoisotopic Mass 275.14408
InChI InChI=1S/C17H21N.ClH/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17;/h3-12,15H,13-14H2,1-2H3;1H/t15-;/m0./s1
InChIKey ANFSNXAXVLRZCG-RSAXXLAASA-N
SMILES [Cl-].C[C@@H](Cc1ccccc1)[NH+](C)Cc1ccccc1
Roles Classification
Biological Role(s): adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Application(s): adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
appetite depressant
Agent that is used to decrease appetite.
dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing benzphetamine hydrochloride (CHEBI:59169) has part benzphetamine (CHEBI:3044)
benzphetamine hydrochloride (CHEBI:59169) has role adrenergic uptake inhibitor (CHEBI:35640)
benzphetamine hydrochloride (CHEBI:59169) has role appetite depressant (CHEBI:50507)
benzphetamine hydrochloride (CHEBI:59169) has role dopamine uptake inhibitor (CHEBI:51039)
benzphetamine hydrochloride (CHEBI:59169) has role sympathomimetic agent (CHEBI:35524)
benzphetamine hydrochloride (CHEBI:59169) is a hydrochloride (CHEBI:36807)
IUPAC Name
(2S)-N-benzyl-1-phenylpropan-2-amine hydrochloride (1:1)
Synonyms Sources
(+)-N-benzyl-N,α-dimethylphenethylamine hydrochloride ChemIDplus
(2S)-N-benzyl-1-phenylpropan-2-aminium chloride IUPAC
benzphetamine HCl ChemIDplus
Registry Numbers Types Sources
3917155 Beilstein Registry Number Beilstein
5411-22-3 CAS Registry Number ChemIDplus
Last Modified
19 April 2010