eflornithine (CHEBI:41948)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	eflornithine

ChEBI ID	CHEBI:41948

Definition	A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Stars	This entity has been manually annotated by the ChEBI Team.

Secondary ChEBI IDs	CHEBI:41946, CHEBI:4761

Supplier Information

Download	Molfile XML SDF

Wikipedia	License

Read full article at Wikipedia

Formula

C6H12F2N2O2

Net Charge

Average Mass

182.16850

Monoisotopic Mass

182.08668

InChI

InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)

InChIKey

VLCYCQAOQCDTCN-UHFFFAOYSA-N

SMILES

NCCCC(N)(C(F)F)C(O)=O

Roles Classification
Chemical Role(s):	Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). (via organic amino compound ) Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid )

Biological Role(s):	trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.

Application(s):	trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.

ChEBI Ontology
Outgoing	eflornithine (CHEBI:41948) has functional parent ornithine (CHEBI:18257) eflornithine (CHEBI:41948) has role trypanocidal drug (CHEBI:36335) eflornithine (CHEBI:41948) is a α-amino acid (CHEBI:33704) eflornithine (CHEBI:41948) is a fluoroamino acid (CHEBI:24068)

Incoming	eflornithine hydrochloride monohydrate (CHEBI:4762) has part eflornithine (CHEBI:41948)

IUPAC Names

2,5-diamino-2-(difluoromethyl)pentanoic acid

2-(difluoromethyl)ornithine

Synonyms	Sources
alpha-(Difluoromethyl)-DL-ornithine	DrugCentral
α-difluoromethylornithine	ChemIDplus
ALPHA-DIFLUOROMETHYLORNITHINE	PDBeChem
DFMO	ChemIDplus
DL-Ornithine, 2-(difluoromethyl)-	KEGG COMPOUND
Eflornithine	KEGG COMPOUND

Last Modified

25 May 2018