CHEBI:521051 - (R)-fenfluramine

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ChEBI Name (R)-fenfluramine
ChEBI ID CHEBI:521051
ChEBI ASCII Name (R)-fenfluramine
Definition The R-enantiomer of fenfluramine.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C12H16F3N
Net Charge 0
Average Mass 231.25730
Monoisotopic Mass 231.12348
InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1
InChIKey DBGIVFWFUFKIQN-SECBINFHSA-N
SMILES CCN[C@H](C)Cc1cccc(c1)C(F)(F)F
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): serotonin uptake inhibitor
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
(via fenfluramine )
serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
(via fenfluramine )
Application(s): serotonin uptake inhibitor
A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
(via fenfluramine )
serotonergic agonist
An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
(via fenfluramine )
appetite depressant
Agent that is used to decrease appetite.
(via fenfluramine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (R)-fenfluramine (CHEBI:521051) is a fenfluramine (CHEBI:5000)
(R)-fenfluramine (CHEBI:521051) is enantiomer of (S)-fenfluramine (CHEBI:439329)
Incoming (S)-fenfluramine (CHEBI:439329) is enantiomer of (R)-fenfluramine (CHEBI:521051)
IUPAC Name
(2R)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
INNs Sources
(R)-fenfluramine ChEBI
levofenfluramina ChemIDplus
levofenfluramine ChemIDplus
levofenfluraminum ChemIDplus
Synonyms Sources
(−)-fenfluramine ChEBI
(R)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine ChEBI
Manual Xrefs Databases
DB01191 DrugBank
US3198834 Patent
View more database links
Registry Numbers Types Sources
37577-24-5 CAS Registry Number ChemIDplus
4783711 Beilstein Registry Number Beilstein
Citation Waiting for Citations Type Source
17870541 PubMed citation ChEMBL
Last Modified
12 July 2010