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InChI=1S/CH4O/c1-2/h2H,1H3
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ChEBI
> Main
CHEBI:4912 - etorphine
Main
ChEBI Ontology
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ChEBI Name
etorphine
ChEBI ID
CHEBI:4912
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download
Molfile
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SDF
Find compounds which contain this structure
Find compounds which resemble this structure
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Wikipedia
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Read full article at Wikipedia
Formula
C25H33NO4
Net Charge
0
Average Mass
411.542
Monoisotopic Mass
411.24096
InChI
InChI=1S/C25H33NO4/c1-
5-
8-
22(2,28)
17-
14-
23-
9-
10-
25(17,29-
4)
21-
24(23)
11-
12-
26(3)
18(23)
13-
15-
6-
7-
16(27)
20(30-
21)
19(15)
24/h6-
7,9-
10,17-
18,21,27-
28H,5,8,11-
14H2,1-
4H3/t17-
,18-
,21-
,22-
,23-
,24+,25-
/m1/s1
InChIKey
CAHCBJPUTCKATP-FAWZKKEFSA-N
SMILES
[H][C@@]1(C[C@@]23C=C[C@]1(OC)[C@@H]1OC4=C(O)C=CC5=C4[C@]21CCN(C)[C@@H]3C5)[C@](C)(O)CCC
Roles Classification
Biological Role
(s):
opioid analgesic
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
opioid receptor agonist
An agent that selectively binds to and activates an opioid receptor.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via
alkaloid
)
Application
(s):
opioid analgesic
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
sedative
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
opioid receptor agonist
An agent that selectively binds to and activates an opioid receptor.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
etorphine (
CHEBI:4912
)
has role
opioid analgesic (
CHEBI:35482
)
etorphine (
CHEBI:4912
)
has role
opioid receptor agonist (
CHEBI:60606
)
etorphine (
CHEBI:4912
)
has role
sedative (
CHEBI:35717
)
etorphine (
CHEBI:4912
)
is a
alcohol (
CHEBI:30879
)
etorphine (
CHEBI:4912
)
is a
morphinane alkaloid (
CHEBI:25418
)
IUPAC Name
(7
R
)-
7-
[(2
R
)-
2-
hydroxypentan-
2-
yl]-
6-
methoxy-
17-
methyl-
5α-
4,5-
epoxy-
6,14-
ethenomorphinan-
3-
ol
INNs
Sources
etorfina
WHO MedNet
étorphine
WHO MedNet
etorphine
WHO MedNet
etorphinum
WHO MedNet
Synonyms
Sources
(−)-etorphine
ChemIDplus
19-Propylorvinol
ChemIDplus
7,8-
Dihydro-
7-
alpha-
(1-
(
R
)-
hydroxy-
1-
methylbutyl)-
O
(sup 6)-
methyl-
6,14-
endo-
ethenomorphine
ChemIDplus
7-alpha-(1-(
R
)-Hydroxy-1-methylbutyl)-6,14-endo-ethenotetrahydrooripavine
ChemIDplus
7α-Etorphine
ChemIDplus
Tetrahydro-7-alpha-(2-hydroxy-2-pentyl)-6,14-endo-ethenooripavine
ChemIDplus
Manual Xrefs
Databases
BE618392
Patent
C11793
KEGG COMPOUND
D07937
KEGG DRUG
DB01497
DrugBank
Etorphine
Wikipedia
GB937214
Patent
US3763167
Patent
View more database links
Registry Numbers
Types
Sources
14521-96-1
CAS Registry Number
NIST Chemistry WebBook
14521-96-1
CAS Registry Number
ChemIDplus
4920991
Beilstein Registry Number
Beilstein
Citations
Types
Sources
25644810
PubMed citation
Europe PMC
26667531
PubMed citation
Europe PMC
26878827
PubMed citation
Europe PMC
27531058
PubMed citation
Europe PMC
27691936
PubMed citation
Europe PMC
27691950
PubMed citation
Europe PMC
28051570
PubMed citation
Europe PMC
28828865
PubMed citation
Europe PMC
28978715
PubMed citation
Europe PMC
29242121
PubMed citation
Europe PMC
30592907
PubMed citation
Europe PMC
30693492
PubMed citation
Europe PMC
30993028
PubMed citation
Europe PMC
31176572
PubMed citation
Europe PMC
31799283
PubMed citation
Europe PMC
32085568
PubMed citation
Europe PMC
32507718
PubMed citation
Europe PMC
4962749
PubMed citation
Europe PMC
Last Modified
06 October 2020