LY294002 (CHEBI:65329)

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ChEBI Name	LY294002

ChEBI ID	CHEBI:65329

Definition	A chromone substituted with a phenyl group at position 8 and a morpholine group at position 2.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C19H17NO3

Net Charge

Average Mass

307.34320

Monoisotopic Mass

307.12084

InChI

InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2

InChIKey

CZQHHVNHHHRRDU-UHFFFAOYSA-N

SMILES

O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1

Roles Classification
Biological Role(s):	autophagy inhibitor Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell). EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.

Application(s):	geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.

ChEBI Ontology
Outgoing	LY294002 (CHEBI:65329) has role autophagy inhibitor (CHEBI:88230) LY294002 (CHEBI:65329) has role EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor (CHEBI:50914) LY294002 (CHEBI:65329) has role geroprotector (CHEBI:176497) LY294002 (CHEBI:65329) is a chromones (CHEBI:23238) LY294002 (CHEBI:65329) is a morpholines (CHEBI:38785) LY294002 (CHEBI:65329) is a organochlorine compound (CHEBI:36683)

IUPAC Name

2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one

Synonyms	Sources
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	ChemIDplus
2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	KEGG COMPOUND
LY 294002	KEGG COMPOUND

Last Modified

27 October 2021