CHEBI:65619 - chloropeptin II

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name chloropeptin II
ChEBI ID CHEBI:65619
Definition A heterodetic cyclic peptide consisting of N-acylated trytophan, 3,5-dichloro-4-hydroxyphenylglycine, 4-hydroxyphenylglycine, 3,5-dichloro-4-hydroxyphenylglycyl, tyrosine and 4-hydroxyphenylglycine residues joined in sequence and in which the side-chain of the central 4-hydroxyphenylglycine residue is attached to the side-chain of the tryptophan via a C3-C6 bond and to the side-chain of the tyrosine via an ether bond from C5. It is isolated from the culture broth of Streptomyces and has anti-HIV-1 activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C61H45Cl6N7O15
Net Charge 0
Average Mass 1328.76600
Monoisotopic Mass 1325.11048
InChI InChI=1S/C61H45Cl6N7O15/c1-74-44(56(82)73-49(61(87)88)25-4-7-32(75)8-5-25)12-24-2-9-33(10-3-24)89-45-22-27-13-35(51(45)77)26-6-11-34-31(23-68-42(34)20-26)21-43(69-59(85)50(76)30-18-40(66)54(80)41(67)19-30)55(81)70-47(28-14-36(62)52(78)37(63)15-28)57(83)71-46(27)58(84)72-48(60(74)86)29-16-38(64)53(79)39(65)17-29/h2-11,13-20,22-23,43-44,46-49,68,75,77-80H,12,21H2,1H3,(H,69,85)(H,70,81)(H,71,83)(H,72,84)(H,73,82)(H,87,88)/t43-,44+,46-,47-,48-,49-/m1/s1
InChIKey JJGZGELTZPACID-OTLJHNKQSA-N
SMILES [H][C@@]12NC(=O)[C@H](NC(=O)[C@@H](Cc3c[nH]c4cc(ccc34)-c3cc1cc(Oc1ccc(C[C@H](N(C)C(=O)[C@H](NC2=O)c2cc(Cl)c(O)c(Cl)c2)C(=O)N[C@@H](C(O)=O)c2ccc(O)cc2)cc1)c3O)NC(=O)C(=O)c1cc(Cl)c(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1
Metabolite of Species Details
Streptomyces sp. (NCBI:txid1931) See: PubMed
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): anti-HIV-1 agent
An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via peptide antibiotic )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing chloropeptin II (CHEBI:65619) has role anti-HIV-1 agent (CHEBI:64947)
chloropeptin II (CHEBI:65619) has role antimicrobial agent (CHEBI:33281)
chloropeptin II (CHEBI:65619) has role metabolite (CHEBI:25212)
chloropeptin II (CHEBI:65619) is a cyclic ether (CHEBI:37407)
chloropeptin II (CHEBI:65619) is a heterodetic cyclic peptide (CHEBI:24533)
chloropeptin II (CHEBI:65619) is a indoles (CHEBI:24828)
chloropeptin II (CHEBI:65619) is a organochlorine compound (CHEBI:36683)
chloropeptin II (CHEBI:65619) is a peptide antibiotic (CHEBI:25903)
chloropeptin II (CHEBI:65619) is a polyphenol (CHEBI:26195)
Synonyms Sources
α-(((8,13-bis(3,5-dichloro-4-hydroxyphenyl)-5-(((3,5-dichloro-4-hydroxyphenyl)oxoacetyl)amino)-2,4,5,6,7,8,9,10,10a,11,12,13,14,15,16,17-hexadecahydro-31-hydroxy-15-methyl-6,9,11,14-tetraoxo-18,21-etheno-1,27:23,26-dimethenopyrrolo(3',4':12,13)(1,4)diazacyclohexadecino(6,5-d)(1,7,10)oxadiazacyclohexadecin-16-yl)carbonyl)amino)-4-hydroxyphenylacetic acid ChemIDplus
Complestatin ChemIDplus
Manual Xrefs Databases
C00016684 KNApSAcK
C15695 KEGG COMPOUND
View more database links
Registry Numbers Types Sources
20323892 Reaxys Registry Number Reaxys
69598-75-0 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
9066767 PubMed citation Europe PMC
Last Modified
04 August 2014