etidronic acid (CHEBI:4907)

ChEBI > Main

Main

ChEBI Ontology

Automatic Xrefs

Reactions

Pathways

Models

ChEBI Name	etidronic acid

ChEBI ID	CHEBI:4907

Definition	A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Anonymous

Secondary ChEBI IDs	CHEBI:63588

Supplier Information

Download	Molfile XML SDF

Wikipedia	License

Read full article at Wikipedia

Formula

C2H8O7P2

Net Charge

Average Mass

206.02820

Monoisotopic Mass

205.97453

InChI

InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)

InChIKey

DBVJJBKOTRCVKF-UHFFFAOYSA-N

SMILES

CC(O)(P(O)(O)=O)P(O)(O)=O

Roles Classification
Chemical Role(s):	chelator A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. bone density conservation agent An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.

ChEBI Ontology
Outgoing	etidronic acid (CHEBI:4907) has role antineoplastic agent (CHEBI:35610) etidronic acid (CHEBI:4907) has role bone density conservation agent (CHEBI:50646) etidronic acid (CHEBI:4907) has role chelator (CHEBI:38161) etidronic acid (CHEBI:4907) is a 1,1-bis(phosphonic acid) (CHEBI:77383) etidronic acid (CHEBI:4907) is conjugate acid of etidronic acid(2−) (CHEBI:77356)

Incoming	etidronic acid(2−) (CHEBI:77356) is conjugate base of etidronic acid (CHEBI:4907)

IUPAC Name

(1-hydroxyethane-1,1-diyl)bis(phosphonic acid)

Synonyms	Sources
(1-Hydroxyethylene)diphosphonic acid	ChemIDplus
(1-Hydroxyethylidene)bis(phosphonic acid)	ChemIDplus
(1-Hydroxyethylidene)bisphosphonic acid	ChemIDplus
(1-Hydroxyethylidene)diphosphonic acid	ChemIDplus
(Hydroxyethylidene)diphosphonic acid	ChemIDplus
1,1,1-Ethanetriol diphosphonate	ChemIDplus
1-Hydroxy-1,1-diphosphonoethane	ChemIDplus
1-Hydroxyethane-1,1-bisphosphonic acid	ChemIDplus
1-Hydroxyethane-1,1-diphosphonate	ChemIDplus
1-Hydroxyethane-1,1-diphosphonic acid	ChemIDplus
1-Hydroxyethanediphosphonic acid	ChemIDplus
1-Hydroxyethylidene-1,1-bisphosphonate	ChemIDplus
1-Hydroxyethylidene-1,1-diphosphonic acid	KEGG COMPOUND
1-Hydroxyethylidene-1,1-diphosphonic acid	ChemIDplus
Acetodiphosphonic acid	DrugBank
EHDP	DrugBank
ethane-1-hydroxy-1,1-bisphosphonic acid	ChEBI
Ethane-1-hydroxy-1,1-diphosphonate	ChemIDplus
Ethane-1-hydroxy-1,1-diphosphonic acid	ChemIDplus
etidronate	ChEBI
Etidronsäure	DrugBank
HEDP	DrugBank
Hydroxyethanediphosphonic acid	DrugBank
Oxyethylidenediphosphonic acid	DrugBank

Last Modified

22 February 2017

General Comment
2014-05-13	Etidronic acid can be found in blood and urine samples of individuals who have taken this drug.