CG-1521 (CHEBI:156510)

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ChEBI Name	CG-1521

ChEBI ID	CHEBI:156510

Definition	An enamide resulting from the formal condensation of the carboxy group of (2E,4E,6E)-7-phenylhepta-2,4,6-trienoic acid with the amino group of hydroxylamine. It is an inhibitor of histone deacetylase (HDAC) which exhibits anticancer properties.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Micheal Alexander

Supplier Information

Download	Molfile XML SDF

Formula

C13H13NO2

Net Charge

Average Mass

215.252

Monoisotopic Mass

215.09463

InChI

InChI=1S/C13H13NO2/c15-13(14-16)11-7-2-1-4-8-12-9-5-3-6-10-12/h1-11,16H,(H,14,15)/b2-1+,8-4+,11-7+

InChIKey

DBBYYRWVNDQECM-CDWOPPGASA-N

SMILES

ONC(=O)\C=C\C=C\C=C\C1=CC=CC=C1

Roles Classification
Biological Role(s):	apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. EC 3.5.1.98 (histone deacetylase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	CG-1521 (CHEBI:156510) has role antineoplastic agent (CHEBI:35610) CG-1521 (CHEBI:156510) has role apoptosis inducer (CHEBI:68495) CG-1521 (CHEBI:156510) has role EC 3.5.1.98 (histone deacetylase) inhibitor (CHEBI:61115) CG-1521 (CHEBI:156510) is a enamide (CHEBI:51751) CG-1521 (CHEBI:156510) is a hydroxamic acid (CHEBI:24650) CG-1521 (CHEBI:156510) is a monocarboxylic acid amide (CHEBI:29347)

IUPAC Name

(2E,4E,6E)-N-hydroxy-7-phenylhepta-2,4,6-trienamide

Synonyms	Sources
(2E,4E,6E)-N-hydroxy-7-phenyl-2,4,6-heptatrienamide	ChemIDplus
CG-1521	ChemIDplus
JW-1521	ChEBI

Registry Number	Type	Source
674767-29-4	CAS Registry Number	ChemIDplus

Last Modified

18 September 2020