CHEBI:3044 - benzphetamine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name benzphetamine
ChEBI ID CHEBI:3044
Definition Dextroamphetamine in which the the hydrogens attached to the amino group are substituted by a methyl and a benzyl group. A sympathomimetic agent with properties similar to dextroamphetamine, it is used as its hydrochloride salt in the treatment of obesity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C17H21N
Net Charge 0
Average Mass 239.35530
Monoisotopic Mass 239.16740
InChI InChI=1S/C17H21N/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17/h3-12,15H,13-14H2,1-2H3/t15-/m0/s1
InChIKey YXKTVDFXDRQTKV-HNNXBMFYSA-N
SMILES C[C@@H](Cc1ccccc1)N(C)Cc1ccccc1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Application(s): sympathomimetic agent
A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
dopamine uptake inhibitor
A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
appetite depressant
Agent that is used to decrease appetite.
adrenergic uptake inhibitor
Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
central nervous system stimulant
Any drug that enhances the activity of the central nervous system.
(via amphetamines )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing benzphetamine (CHEBI:3044) has role adrenergic uptake inhibitor (CHEBI:35640)
benzphetamine (CHEBI:3044) has role appetite depressant (CHEBI:50507)
benzphetamine (CHEBI:3044) has role dopamine uptake inhibitor (CHEBI:51039)
benzphetamine (CHEBI:3044) has role sympathomimetic agent (CHEBI:35524)
benzphetamine (CHEBI:3044) is a amphetamines (CHEBI:35338)
benzphetamine (CHEBI:3044) is a tertiary amine (CHEBI:32876)
Incoming benzphetamine hydrochloride (CHEBI:59169) has part benzphetamine (CHEBI:3044)
IUPAC Name
(2S)-N-benzyl-N-methyl-1-phenylpropan-2-amine
INNs Sources
benzfetamina ChemIDplus
benzfetamine KEGG DRUG
benzfetaminum ChemIDplus
Synonyms Sources
(+)-benzphetamine ChEBI
(+)-N,α-dimethyl-N-(phenylmethyl)-benzeneethanamine ChEBI
(+)-N-benzyl-N,α-dimethylphenethylamine ChEBI
(αS)-N,α-dimethylphenethylamine ChEBI
(S)-(+)-benzphetamine ChEBI
(S)-(+)-N-benzyl-N,α-dimethylphenethylamine ChEBI
(S)-benzphetamine ChEBI
benzaphetamine NIST Chemistry WebBook
Benzfetamine KEGG COMPOUND
Benzphetamine KEGG COMPOUND
benzylamphetamine DrugBank
d-N-methyl-N-benzyl-β-phenylisopropylamine ChEBI
N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine DrugBank
Manual Xrefs Databases
329 DrugCentral
C07538 KEGG COMPOUND
D07514 KEGG DRUG
DB00865 DrugBank
US2789138 Patent
View more database links
Registry Numbers Types Sources
156-08-1 CAS Registry Number NIST Chemistry WebBook
156-08-1 CAS Registry Number ChemIDplus
3203999 Beilstein Registry Number Beilstein
Last Modified
22 February 2017