CHEBI:64199 - carmoxirole hydrochloride

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name carmoxirole hydrochloride
ChEBI ID CHEBI:64199
Definition A hydrochloride salt obtained by reaction of carmoxirole with one equivalent of hydrochloric acid. Selective, peripherally acting dopamine D2 receptor agonist. Modulates noradrenalin release and sympathetic activation. Displays antihypertensive properties in vivo.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
more structures >>
Formula C24H27ClN2O2
Net Charge 0
Average Mass 410.93600
Monoisotopic Mass 410.17611
InChI InChI=1S/C24H26N2O2.ClH/c27-24(28)20-9-10-23-22(16-20)21(17-25-23)8-4-5-13-26-14-11-19(12-15-26)18-6-2-1-3-7-18;/h1-3,6-7,9-11,16-17,25H,4-5,8,12-15H2,(H,27,28);1H
InChIKey LRJUHOBITQUXIO-UHFFFAOYSA-N
SMILES Cl.OC(=O)c1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1
Roles Classification
Biological Role(s): dopamine agonist
A drug that binds to and activates dopamine receptors.
Application(s): dopamine agonist
A drug that binds to and activates dopamine receptors.
antihypertensive agent
Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing carmoxirole hydrochloride (CHEBI:64199) has part carmoxirole(1+) (CHEBI:64201)
carmoxirole hydrochloride (CHEBI:64199) has role antihypertensive agent (CHEBI:35674)
carmoxirole hydrochloride (CHEBI:64199) has role dopamine agonist (CHEBI:51065)
carmoxirole hydrochloride (CHEBI:64199) has role platelet aggregation inhibitor (CHEBI:50427)
carmoxirole hydrochloride (CHEBI:64199) is a hydrochloride (CHEBI:36807)
IUPAC Name
3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indole-5-carboxylic acid hydrochloride
Synonym Source
1-[4-(5-carboxy-1H-indol-3-yl)butyl]-4-phenyl-1,2,3,6-tetrahydropyridinium chloride IUPAC
Registry Number Type Source
5689787 Reaxys Registry Number Reaxys
Last Modified
16 March 2012