CHEBI:139043 - carbocyclic thromboxane A₂

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ChEBI Name carbocyclic thromboxane A2 ChEBI ID CHEBI:139043 ChEBI ASCII Name carbocyclic thromboxane A2 Definition A member of the class of thromboxanes that is thromboxane A2 in which the bridging oxygen has been replaced by a methylene group. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Formula C21H34O4 Net Charge 0 Average Mass 350.493 Monoisotopic Mass 350.24571 InChI InChI=1S/C21H34O4/c1-2-3-6-9-17(22)12-13-20-19(16-14-18(15-16)25-20)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17-,18+,19-,20+/m0/s1 InChIKey VQUUFWNZZIMDBR-SXNJQZKASA-N SMILES C1[C@H]2[C@@H]([C@H](O[C@@H]1C2)/C=C/[C@H](CCCCC)O)C/C=C\CCCC(=O)O Roles Classification Chemical Role(s): Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). (via oxoacid ) Biological Role(s): thromboxane A2 agonist An agonist that binds to and activates thromboxane A2 receptors. Application(s): vasoconstrictor agent Drug used to cause constriction of the blood vessels. View more via ChEBI Ontology ChEBI Ontology Outgoing carbocyclic thromboxane A2 (CHEBI:139043) has functional parent thromboxane A2 (CHEBI:15627) carbocyclic thromboxane A2 (CHEBI:139043) has role thromboxane A2 agonist (CHEBI:139044) carbocyclic thromboxane A2 (CHEBI:139043) has role vasoconstrictor agent (CHEBI:50514) carbocyclic thromboxane A2 (CHEBI:139043) is a bridged compound (CHEBI:35990) carbocyclic thromboxane A2 (CHEBI:139043) is a cyclic ether (CHEBI:37407) carbocyclic thromboxane A2 (CHEBI:139043) is a hydroxy monocarboxylic acid (CHEBI:35868) carbocyclic thromboxane A2 (CHEBI:139043) is a secondary allylic alcohol (CHEBI:134396) carbocyclic thromboxane A2 (CHEBI:139043) is a thromboxane (CHEBI:26995) carbocyclic thromboxane A2 (CHEBI:139043) is conjugate acid of carbocyclic thromboxane A2(1−) (CHEBI:138322) Incoming 18-hydroxycarbocyclic thromboxane A2 (CHEBI:139046) has functional parent carbocyclic thromboxane A2 (CHEBI:139043) 19-hydroxycarbocyclic thromboxane A2 (CHEBI:139045) has functional parent carbocyclic thromboxane A2 (CHEBI:139043) carbocyclic thromboxane A2(1−) (CHEBI:138322) is conjugate base of carbocyclic thromboxane A2 (CHEBI:139043) IUPAC Name (5Z)-7-{(1R,3R,4S,5R)-3-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[3.1.1]heptan-4-yl}hept-5-enoic acid Synonyms Sources 9α,11α-methylene thromboxane A2 ChEBI 9α,11α-methylene-TXA2 ChEBI carbocyclic TXA2 ChEBI Citations Types Sources 10542977 PubMed citation Europe PMC 11483590 PubMed citation Europe PMC 12614148 PubMed citation Europe PMC 12628222 PubMed citation Europe PMC 1561230 PubMed citation Europe PMC 15789615 PubMed citation Europe PMC 16093422 PubMed citation Europe PMC 16896186 PubMed citation Europe PMC 17109692 PubMed citation Europe PMC 1838696 PubMed citation Europe PMC 3387452 PubMed citation Europe PMC 3512276 PubMed citation Europe PMC 6754126 PubMed citation Europe PMC 6960809 PubMed citation Europe PMC 7591017 PubMed citation Europe PMC 7693541 PubMed citation Europe PMC 7966472 PubMed citation Europe PMC 8135127 PubMed citation Europe PMC 8831114 PubMed citation Europe PMC 9014151 PubMed citation Europe PMC 9342927 PubMed citation Europe PMC Last Modified 15 November 2017