CHEBI:701 - licarbazepine

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ChEBI Name licarbazepine ChEBI ID CHEBI:701 Definition A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine. Stars This entity has been manually annotated by the ChEBI Team. Supplier Information Download Molfile XML SDF Find compounds which contain this structure Find compounds which resemble this structure Take structure to the Advanced Search Wikipedia License Read full article at Wikipedia Formula C15H14N2O2 Net Charge 0 Average Mass 254.28390 Monoisotopic Mass 254.10553 InChI InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19) InChIKey BMPDWHIDQYTSHX-UHFFFAOYSA-N SMILES NC(=O)N1c2ccccc2CC(O)c2ccccc12 Roles Classification Biological Role(s): drug allergen Any drug which causes the onset of an allergic reaction. sodium channel blocker An agent that inhibits sodium influx through cell membranes. Application(s): drug allergen Any drug which causes the onset of an allergic reaction. anticonvulsant A drug used to prevent seizures or reduce their severity. View more via ChEBI Ontology ChEBI Ontology Outgoing licarbazepine (CHEBI:701) has functional parent carbamazepine (CHEBI:3387) licarbazepine (CHEBI:701) has role anticonvulsant (CHEBI:35623) licarbazepine (CHEBI:701) has role drug allergen (CHEBI:88188) licarbazepine (CHEBI:701) has role sodium channel blocker (CHEBI:38633) licarbazepine (CHEBI:701) is a carboxamide (CHEBI:37622) licarbazepine (CHEBI:701) is a dibenzoazepine (CHEBI:47804) licarbazepine (CHEBI:701) is a ureas (CHEBI:47857) Incoming eslicarbazepine acetate (CHEBI:87016) has functional parent licarbazepine (CHEBI:701) IUPAC Name 10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide INN Source licarbazepine ChemIDplus Synonyms Sources 10,11-Dihydro-10-hydroxycarbamazepine ChemIDplus 10-Hydroxycarbamazepine KEGG COMPOUND 10-Hydroxycarbazepine KEGG COMPOUND GP 47779 KEGG COMPOUND Manual Xrefs Databases C07493 KEGG COMPOUND Licarbazepine Wikipedia View more database links Registry Numbers Types Sources 1540211 Reaxys Registry Number Reaxys 29331-92-8 CAS Registry Number ChemIDplus Citations Types Sources 22322005 PubMed citation Europe PMC 23507454 PubMed citation Europe PMC 24123382 PubMed citation Europe PMC 24981999 PubMed citation Europe PMC 25261836 PubMed citation Europe PMC 25489632 PubMed citation Europe PMC Last Modified 12 March 2019