CHEBI:66614 - neobavaisoflavone

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ChEBI Name neobavaisoflavone
Definition A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone with an additonal hydroxy group at position 4' and a prenyl group at position 3'. Isolated from seeds of Psoralea corylifolia, it exhibits inhibitory activity against DNA polymerase and platelet aggregation.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C20H18O4
Net Charge 0
Average Mass 322.35450
Monoisotopic Mass 322.12051
InChI InChI=1S/C20H18O4/c1-12(2)3-4-14-9-13(5-8-18(14)22)17-11-24-19-10-15(21)6-7-16(19)20(17)23/h3,5-11,21-22H,4H2,1-2H3
SMILES CC(C)=CCc1cc(ccc1O)-c1coc2cc(O)ccc2c1=O
Metabolite of Species Details
Psoralea corylifolia (NCBI:txid429560) Found in seed (BTO:0001226). See: PubMed
Roles Classification
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
EC (DNA-directed DNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC
Application(s): platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing neobavaisoflavone (CHEBI:66614) has role antineoplastic agent (CHEBI:35610)
neobavaisoflavone (CHEBI:66614) has role EC (DNA-directed DNA polymerase) inhibitor (CHEBI:131699)
neobavaisoflavone (CHEBI:66614) has role plant metabolite (CHEBI:76924)
neobavaisoflavone (CHEBI:66614) has role platelet aggregation inhibitor (CHEBI:50427)
neobavaisoflavone (CHEBI:66614) is a 7-hydroxyisoflavones (CHEBI:55465)
Incoming 2'-hydroxyneobavaisoflavanone (CHEBI:66048) has functional parent neobavaisoflavone (CHEBI:66614)
Synonyms Sources
7,4'-dihydroxy-3'-(3-methyl-buten-2-yl)isoflavone ChEBI
7,4'-dihydroxy-3'-(γ,γ-dimethylallyl)isoflavone ChEBI
7-hydroxy-3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-4H-1-benzopyran-4-one ChEBI
Manual Xref Database
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Registry Number Type Source
4518386 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
22397994 PubMed citation Europe PMC
23323951 PubMed citation Europe PMC
8759164 PubMed citation Europe PMC
9544566 PubMed citation Europe PMC
Last Modified
07 April 2016