CHEBI:79345 - tafamidis meglumine

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ChEBI Name tafamidis meglumine
Definition An organoammonium salt obtained by combining tafamidis with one molar equivalent of 1-deoxy-1-(methylamino)-D-glucitol. Used for the amelioration of transthyretin-related hereditary amyloidosis.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C21H24Cl2N2O8
Net Charge 0
Average Mass 503.33000
Monoisotopic Mass 502.09097
InChI InChI=1S/C14H7Cl2NO3.C7H17NO5/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-6H,(H,18,19);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
SMILES CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1
Roles Classification
Application(s): central nervous system drug
A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
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ChEBI Ontology
Outgoing tafamidis meglumine (CHEBI:79345) has part tafamidis(1−) (CHEBI:79344)
tafamidis meglumine (CHEBI:79345) has role central nervous system drug (CHEBI:35470)
tafamidis meglumine (CHEBI:79345) is a organoammonium salt (CHEBI:46850)
1-deoxy-1-(methylazaniumyl)-D-glucitol 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylate
2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid—1-deoxy-1-(methylamino)-D-glucitol (1/1)
Synonyms Sources
Fx 1006A ChemIDplus
Fx-1006a ChemIDplus
Fx1006A ChemIDplus
Brand Name Source
Vyndaqel KEGG DRUG
Manual Xrefs Databases
Tafamidis Wikipedia
WO2013038351 Patent
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Registry Numbers Types Sources
23441785 Reaxys Registry Number Reaxys
951395-08-7 CAS Registry Number KEGG DRUG
951395-08-7 CAS Registry Number ChemIDplus
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Last Modified
22 July 2014