CHEBI:79345 - tafamidis meglumine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name tafamidis meglumine
ChEBI ID CHEBI:79345
Definition An organoammonium salt obtained by combining tafamidis with one molar equivalent of 1-deoxy-1-(methylamino)-D-glucitol. Used for the amelioration of transthyretin-related hereditary amyloidosis.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
more structures >>
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C21H24Cl2N2O8
Net Charge 0
Average Mass 503.33000
Monoisotopic Mass 502.09097
InChI InChI=1S/C14H7Cl2NO3.C7H17NO5/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-6H,(H,18,19);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
InChIKey DQJDBUPLRMRBAB-WZTVWXICSA-N
SMILES CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1
Roles Classification
Application(s): central nervous system drug
A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tafamidis meglumine (CHEBI:79345) has part tafamidis(1−) (CHEBI:79344)
tafamidis meglumine (CHEBI:79345) has role central nervous system drug (CHEBI:35470)
tafamidis meglumine (CHEBI:79345) is a organoammonium salt (CHEBI:46850)
IUPAC Names
1-deoxy-1-(methylazaniumyl)-D-glucitol 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylate
2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid—1-deoxy-1-(methylamino)-D-glucitol (1/1)
Synonyms Sources
Fx 1006A ChemIDplus
Fx-1006a ChemIDplus
Fx1006A ChemIDplus
Brand Name Source
Vyndaqel KEGG DRUG
Manual Xrefs Databases
D09674 KEGG DRUG
Tafamidis Wikipedia
WO2013038351 Patent
View more database links
Registry Numbers Types Sources
23441785 Reaxys Registry Number Reaxys
951395-08-7 CAS Registry Number KEGG DRUG
951395-08-7 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
22094129 PubMed citation Europe PMC
22378262 PubMed citation Europe PMC
22645360 PubMed citation Europe PMC
22645721 PubMed citation Europe PMC
23483184 PubMed citation Europe PMC
23776379 PubMed citation Europe PMC
24000164 PubMed citation Europe PMC
24101373 PubMed citation Europe PMC
25022953 PubMed citation Europe PMC
Last Modified
22 July 2014