A member of the class of chalcones that is trans-chalcone substituted by a methyl group at position 3', hydroxy groups at positions 2' and 4' and a methoxy group at position 6'. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.
Stars
This entity has been manually annotated by the ChEBI Team.
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
2',4'-dihydroxy-3'-methyl-6'-methoxychalcone
(CHEBI:70659)
has functional parent
trans-chalcone
(CHEBI:48965)
2',4'-dihydroxy-3'-methyl-6'-methoxychalcone
(CHEBI:70659)
has role
EC 3.2.1.18 (exo-α-sialidase) inhibitor
(CHEBI:52425)
2',4'-dihydroxy-3'-methyl-6'-methoxychalcone
(CHEBI:70659)
has role
plant metabolite
(CHEBI:76924)
2',4'-dihydroxy-3'-methyl-6'-methoxychalcone
(CHEBI:70659)
is a
chalcones
(CHEBI:23086)
2',4'-dihydroxy-3'-methyl-6'-methoxychalcone
(CHEBI:70659)
is a
monomethoxybenzene
(CHEBI:25235)
2',4'-dihydroxy-3'-methyl-6'-methoxychalcone
(CHEBI:70659)
is a
resorcinols
(CHEBI:33572)