9-hydroxycanthin-6-one (CHEBI:66041)

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ChEBI Name	9-hydroxycanthin-6-one

ChEBI ID	CHEBI:66041

Definition	An indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 9. Isolated from the roots of Eurycoma longifolia, it exhibits antineoplastic activity.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C14H8N2O2

Net Charge

Average Mass

236.22550

Monoisotopic Mass

236.05858

InChI

InChI=1S/C14H8N2O2/c17-8-1-2-9-10-5-6-15-11-3-4-13(18)16(14(10)11)12(9)7-8/h1-7,17H

InChIKey

JHPIJMUNSMWWAA-UHFFFAOYSA-N

SMILES

Oc1ccc2c3ccnc4ccc(=O)n(c2c1)c34

Metabolite of Species	Details
Eurycoma longifolia (NCBI:txid458531)	Found in root (BTO:0001188). See: PubMed

Roles Classification
Biological Role(s):	metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. (via alkaloid )

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	9-hydroxycanthin-6-one (CHEBI:66041) has functional parent canthin-6-one (CHEBI:3363) 9-hydroxycanthin-6-one (CHEBI:66041) has role antineoplastic agent (CHEBI:35610) 9-hydroxycanthin-6-one (CHEBI:66041) has role metabolite (CHEBI:25212) 9-hydroxycanthin-6-one (CHEBI:66041) is a indole alkaloid (CHEBI:38958) 9-hydroxycanthin-6-one (CHEBI:66041) is a organic heterotetracyclic compound (CHEBI:38163)

IUPAC Name

9-hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one

Registry Number	Type	Source
5340229	Reaxys Registry Number	Reaxys

Last Modified

07 November 2013