CHEBI:31368 - cefepime hydrochloride

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ChEBI Name cefepime hydrochloride
Definition A hydrochloride that is the monohydrate of the dihydrochloride salt of cefepime.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C19H28Cl2N6O6S2
Net Charge 0
Average Mass 571.49800
Monoisotopic Mass 570.08888
InChI InChI=1S/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H;1H2/b23-12-;;;/t13-,17-;;;/m1.../s1
SMILES O.Cl.[Cl-].[H][C@]12SCC(C[N+]3(C)CCCC3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O
Roles Classification
Biological Role(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
drug allergen
Any drug which causes the onset of an allergic reaction.
(via cephalosporin )
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via heterocyclic antibiotic )
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
drug allergen
Any drug which causes the onset of an allergic reaction.
(via cephalosporin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing cefepime hydrochloride (CHEBI:31368) has part cefepime(1+) (CHEBI:59349)
cefepime hydrochloride (CHEBI:31368) has role antibacterial drug (CHEBI:36047)
cefepime hydrochloride (CHEBI:31368) is a cephalosporin (CHEBI:23066)
cefepime hydrochloride (CHEBI:31368) is a hydrate (CHEBI:35505)
cefepime hydrochloride (CHEBI:31368) is a hydrochloride (CHEBI:36807)
1-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidinium chloride hydrochloride—water (1/1)
7β-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylpyrrolidinium-1-yl)methyl]-3,4-didehydrocepham-4-carboxylic acid chloride hydrochloride—water (1/1)
Synonyms Sources
1-(((6R,7R)-7-(2-(2-amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3- yl)methyl)-1-methylpyrrolidinium chloride, 72-(Z)-(O-methyloxime) monohydrochloride monohydrate ChemIDplus
Cefepime dihydrochloride KEGG COMPOUND
cefepime dihydrochloride monohydrate ChEBI
cefepime HCl ChemIDplus
Cefepime hydrochloride KEGG COMPOUND
cefepime hydrochloride hydrate ChEBI
Manual Xrefs Databases
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Registry Numbers Types Sources
123171-59-5 CAS Registry Number KEGG COMPOUND
123171-59-5 CAS Registry Number ChemIDplus
Last Modified
18 March 2011
General Comment
2011-03-18 A semi-synthetic fourth-generation cephalosporin antibiotic, cefepime hydrochloride shows greater activity than third-generation agents against both Gram-positive and Gram-negative organisms, and is used for treatment of severe nosocomial pneumonia, infections caused by multi-resistant microorganisms (e.g. Pseudomonas aeruginosa) and empirical treatment of febrile neutropenia.