2-oxoglutarate(2-) (CHEBI:16810)

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ChEBI Name	2-oxoglutarate(2−)

ChEBI ID	CHEBI:16810

ChEBI ASCII Name	2-oxoglutarate(2-)

Definition	An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid.

Stars	This entity has been manually annotated by the ChEBI Team.

Secondary ChEBI IDs	CHEBI:11638, CHEBI:19748

Supplier Information

Download	Molfile XML SDF

Formula

C5H4O5

Net Charge

-2

Average Mass

144.08226

Monoisotopic Mass

144.00697

InChI

InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)/p-2

InChIKey

KPGXRSRHYNQIFN-UHFFFAOYSA-L

SMILES

[O-]C(=O)CCC(=O)C([O-])=O

Metabolite of Species	Details
Chlamydomonas reinhardtii (NCBI:txid3055)	See: PubMed
Saccharomyces cerevisiae (NCBI:txid4932)	Source: yeast.sf.net See: PubMed
Homo sapiens (NCBI:txid9606)	See: DOI

Roles Classification
Biological Role(s):	Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). algal metabolite Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.

Application(s):	geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.

ChEBI Ontology
Outgoing	2-oxoglutarate(2−) (CHEBI:16810) has functional parent glutarate(2−) (CHEBI:30921) 2-oxoglutarate(2−) (CHEBI:16810) has role Saccharomyces cerevisiae metabolite (CHEBI:75772) 2-oxoglutarate(2−) (CHEBI:16810) has role algal metabolite (CHEBI:84735) 2-oxoglutarate(2−) (CHEBI:16810) has role geroprotector (CHEBI:176497) 2-oxoglutarate(2−) (CHEBI:16810) has role human metabolite (CHEBI:77746) 2-oxoglutarate(2−) (CHEBI:16810) is a oxo dicarboxylate (CHEBI:36147) 2-oxoglutarate(2−) (CHEBI:16810) is conjugate base of 2-oxoglutarate(1−) (CHEBI:30916)

Incoming	2-oxoglutarate(1−) (CHEBI:30916) is conjugate acid of 2-oxoglutarate(2−) (CHEBI:16810)

IUPAC Name

2-oxopentanedioate

Last Modified

28 October 2021