CHEBI:50683 - EC 1.5.1.3 (dihydrofolate reductase) inhibitor

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name EC 1.5.1.3 (dihydrofolate reductase) inhibitor
ChEBI ID CHEBI:50683
Definition An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3).
Stars This entity has been manually annotated by the ChEBI Team.
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ChEBI Ontology
Outgoing EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683) is a antifolate (CHEBI:73913)
EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683) is a EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD+ or NADP+ as acceptor) inhibitor (CHEBI:76863)
Incoming (R)-iclaprim (CHEBI:131752) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
(S)-iclaprim (CHEBI:131753) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
4-aminofolic acid (CHEBI:22526) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
O-(chloroacetylcarbamoyl)fumagillol (CHEBI:90748) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
brodimoprim (CHEBI:131726) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
cycloguanil (CHEBI:135029) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
iclaprim (CHEBI:131724) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
methotrexate (CHEBI:44185) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
methotrexate disodium (CHEBI:50679) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
pemetrexed (CHEBI:63616) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
pemetrexed disodium (CHEBI:63722) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
pemetrexed disodium heptahydrate (CHEBI:63723) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
pralatrexate (CHEBI:71223) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
proguanil (CHEBI:8455) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
pyrimethamine (CHEBI:8673) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
triclosan (CHEBI:164200) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
trimethoprim (CHEBI:45924) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
Synonyms Sources
7,8-dihydrofolate reductase inhibitor ChEBI
7,8-dihydrofolate reductase inhibitors ChEBI
DHFR inhibitor ChEBI
DHFR inhibitors ChEBI
dihydrofolate reductase (EC 1.5.1.3) inhibitor ChEBI
dihydrofolate reductase (EC 1.5.1.3) inhibitors ChEBI
dihydrofolate reductase inhibitor ChEBI
dihydrofolate reductase inhibitors ChEBI
dihydrofolic acid reductase inhibitor ChEBI
dihydrofolic acid reductase inhibitors ChEBI
dihydrofolic reductase inhibitor ChEBI
dihydrofolic reductase inhibitors ChEBI
EC 1.5.1.3 (dihydrofolate reductase) inhibitors ChEBI
EC 1.5.1.3 inhibitor ChEBI
EC 1.5.1.3 inhibitors ChEBI
folic acid reductase inhibitor ChEBI
folic acid reductase inhibitors ChEBI
folic reductase inhibitor ChEBI
folic reductase inhibitors ChEBI
NADPH-dihydrofolate reductase inhibitor ChEBI
NADPH-dihydrofolate reductase inhibitors ChEBI
tetrahydrofolate dehydrogenase inhibitor ChEBI
tetrahydrofolate dehydrogenase inhibitors ChEBI
Manual Xref Database
Dihydrofolate_reductase_inhibitor Wikipedia
View more database links
Last Modified
21 June 2018