CHEBI:9399 - tamsulosin hydrochloride

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ChEBI Name tamsulosin hydrochloride
ChEBI ID CHEBI:9399
Definition A hydrochloride resulting from the reaction of equimolar amounts of tamulosin and hydrogen chloride.
Stars This entity has been manually annotated by the ChEBI Team.
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Formulae C20H28N2O5S.HCl
C20H29ClN2O5S
Net Charge 0
Average Mass 444.974
Monoisotopic Mass 444.14857
InChI InChI=1S/C20H28N2O5S.ClH/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24;/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24);1H/t15-;/m1./s1
InChIKey ZZIZZTHXZRDOFM-XFULWGLBSA-N
SMILES C=1C=C(OCCN[C@@H](CC2=CC=C(C(=C2)S(N)(=O)=O)OC)C)C(=CC1)OCC.Cl
Roles Classification
Biological Role(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Application(s): alpha-adrenergic antagonist
An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tamsulosin hydrochloride (CHEBI:9399) has part tamsulosin(1+) (CHEBI:142544)
tamsulosin hydrochloride (CHEBI:9399) has role α-adrenergic antagonist (CHEBI:37890)
tamsulosin hydrochloride (CHEBI:9399) has role antineoplastic agent (CHEBI:35610)
tamsulosin hydrochloride (CHEBI:9399) is a hydrochloride (CHEBI:36807)
tamsulosin hydrochloride (CHEBI:9399) is enantiomer of ent-tamsulosin hydrochloride (CHEBI:142550)
Incoming rac-tamsulosin hydrochloride (CHEBI:142565) has part tamsulosin hydrochloride (CHEBI:9399)
rac-tamulosin hydrochloride (CHEBI:142553) has part tamsulosin hydrochloride (CHEBI:9399)
ent-tamsulosin hydrochloride (CHEBI:142550) is enantiomer of tamsulosin hydrochloride (CHEBI:9399)
IUPAC Name
5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide hydrochloride
Synonyms Sources
(−)-(R)-5-(2-((2-(o-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide monohydrochloride ChemIDplus
LY253351 ChemIDplus
R-(−)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide hydrochloride ChemIDplus
YM 617 ChemIDplus
Brand Names Sources
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide monohydrochloride ChemIDplus
Flomax KEGG DRUG
Harnal KEGG DRUG
Omnic ChemIDplus
Pradif ChemIDplus
Manual Xrefs Databases
2562 DrugCentral
D01024 KEGG DRUG
DB00706 DrugBank
WO2007031823 Patent
View more database links
Registry Numbers Types Sources
106463-17-6 CAS Registry Number ChemIDplus
6897600 Beilstein Registry Number Beilstein
Last Modified
13 November 2018