CHEBI:69019 - physalin F

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ChEBI Name physalin F
ChEBI ID CHEBI:69019
Definition A physalin with antimalarial and antitumour activities isolated from Physalis angulata.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C28H30O10
Net Charge 0
Average Mass 526.53180
Monoisotopic Mass 526.18390
InChI InChI=1S/C28H30O10/c1-22-10-17-24(3)28-18(22)19(30)27(38-28,34-11-14(22)20(31)35-17)13-9-16-26(36-16)7-4-5-15(29)23(26,2)12(13)6-8-25(28,33)21(32)37-24/h4-5,12-14,16-18,33H,6-11H2,1-3H3/t12-,13+,14-,16+,17+,18-,22+,23-,24-,25+,26+,27+,28-/m0/s1
InChIKey VSLWNSSUMFSGFF-DKOLRWHASA-N
SMILES C[C@@]12OC(=O)[C@]3(O)CC[C@H]4[C@@H](C[C@H]5O[C@]55CC=CC(=O)[C@]45C)[C@@]45O[C@@]13[C@@H](C4=O)[C@]1(C)C[C@H]2OC(=O)[C@@H]1CO5
Metabolite of Species Details
Physalis angulata (NCBI:txid113208) See: PubMed
Roles Classification
Biological Role(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
(via physalin )
Application(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing physalin F (CHEBI:69019) has role antileishmanial agent (CHEBI:70868)
physalin F (CHEBI:69019) has role antimalarial (CHEBI:38068)
physalin F (CHEBI:69019) has role antineoplastic agent (CHEBI:35610)
physalin F (CHEBI:69019) has role apoptosis inducer (CHEBI:68495)
physalin F (CHEBI:69019) has role immunosuppressive agent (CHEBI:35705)
physalin F (CHEBI:69019) is a enone (CHEBI:51689)
physalin F (CHEBI:69019) is a epoxy steroid (CHEBI:145217)
physalin F (CHEBI:69019) is a lactone (CHEBI:25000)
physalin F (CHEBI:69019) is a physalin (CHEBI:76361)
Synonyms Sources
5,6-epxoyphysalin B ChemIDplus
5β,6β-epoxy-5,6-dihydrophysalin B ChEBI
Manual Xref Database
HMDB0034092 HMDB
View more database links
Registry Numbers Types Sources
1696575 Reaxys Registry Number Reaxys
57423-71-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1503404 PubMed citation Europe PMC
15888378 PubMed citation Europe PMC
1622143 PubMed citation Europe PMC
19454526 PubMed citation Europe PMC
20681573 PubMed citation Europe PMC
21954931 PubMed citation Europe PMC
22815798 PubMed citation Europe PMC
24051023 PubMed citation Europe PMC
Last Modified
29 October 2019