phenylarsine oxide (CHEBI:75253)

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ChEBI Name	phenylarsine oxide

ChEBI ID	CHEBI:75253

Definition	An arsine oxide derived from phenylarsine.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information

Download	Molfile XML SDF

Formula

C6H5AsO

Net Charge

Average Mass

168.02490

Monoisotopic Mass

167.95564

InChI

InChI=1S/C6H5AsO/c8-7-6-4-2-1-3-5-6/h1-5H

InChIKey

BQVCCPGCDUSGOE-UHFFFAOYSA-N

SMILES

O=[As]c1ccccc1

Roles Classification
Biological Role(s):	EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins. apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.

Application(s):	antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	phenylarsine oxide (CHEBI:75253) has role antineoplastic agent (CHEBI:35610) phenylarsine oxide (CHEBI:75253) has role apoptosis inducer (CHEBI:68495) phenylarsine oxide (CHEBI:75253) has role EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor (CHEBI:35608) phenylarsine oxide (CHEBI:75253) is a arsine oxides (CHEBI:35843)

IUPAC Name

oxo(phenyl)arsine

Last Modified

19 August 2013