CHEBI:2979 - baicalein

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name baicalein
ChEBI ID CHEBI:2979
Definition A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C15H10O5
Net Charge 0
Average Mass 270.240
Monoisotopic Mass 270.05282
InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChIKey FXNFHKRTJBSTCS-UHFFFAOYSA-N
SMILES OC1=C(O)C(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1
Metabolite of Species Details
Lepisorus ussuriensis (NCBI:txid699700) Found in whole plant (BTO:0001461). See: PubMed
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
radical scavenger
A role played by a substance that can react readily with, and thereby eliminate, radicals.
Biological Role(s): hormone antagonist
A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
prostaglandin antagonist
A compound that inhibits the action of prostaglandins.
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26).
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor
A lipoxygenase inhibitor that interferes with the action of arachidonate 12-lipoxygenase (EC 1.13.11.31).
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor
A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33).
ferroptosis inhibitor
Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
anticoronaviral agent
Any antiviral agent which inhibits the activity of coronaviruses.
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor
An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69).
EC 4.1.1.17 (ornithine decarboxylase) inhibitor
An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ornithine decarboxylase (EC 4.1.1.17).
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
Application(s): hormone antagonist
A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
prostaglandin antagonist
A compound that inhibits the action of prostaglandins.
geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
angiogenesis inhibitor
An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing baicalein (CHEBI:2979) has role angiogenesis inhibitor (CHEBI:48422)
baicalein (CHEBI:2979) has role anti-inflammatory agent (CHEBI:67079)
baicalein (CHEBI:2979) has role antibacterial agent (CHEBI:33282)
baicalein (CHEBI:2979) has role anticoronaviral agent (CHEBI:149553)
baicalein (CHEBI:2979) has role antifungal agent (CHEBI:35718)
baicalein (CHEBI:2979) has role antineoplastic agent (CHEBI:35610)
baicalein (CHEBI:2979) has role antioxidant (CHEBI:22586)
baicalein (CHEBI:2979) has role apoptosis inducer (CHEBI:68495)
baicalein (CHEBI:2979) has role EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor (CHEBI:64995)
baicalein (CHEBI:2979) has role EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor (CHEBI:64996)
baicalein (CHEBI:2979) has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor (CHEBI:76779)
baicalein (CHEBI:2979) has role EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor (CHEBI:147285)
baicalein (CHEBI:2979) has role EC 4.1.1.17 (ornithine decarboxylase) inhibitor (CHEBI:139556)
baicalein (CHEBI:2979) has role ferroptosis inhibitor (CHEBI:173084)
baicalein (CHEBI:2979) has role geroprotector (CHEBI:176497)
baicalein (CHEBI:2979) has role hormone antagonist (CHEBI:49020)
baicalein (CHEBI:2979) has role plant metabolite (CHEBI:76924)
baicalein (CHEBI:2979) has role prostaglandin antagonist (CHEBI:49023)
baicalein (CHEBI:2979) has role radical scavenger (CHEBI:48578)
baicalein (CHEBI:2979) is a trihydroxyflavone (CHEBI:27116)
baicalein (CHEBI:2979) is conjugate acid of baicalein(1−) (CHEBI:78324)
Incoming 5,6,7-trimethoxyflavone (CHEBI:2980) has functional parent baicalein (CHEBI:2979)
baicalin (CHEBI:2981) has functional parent baicalein (CHEBI:2979)
baicalein(1−) (CHEBI:78324) is conjugate base of baicalein (CHEBI:2979)
IUPAC Name
5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
Synonyms Sources
5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one IUPAC
5,6,7-Trihydroxyflavone KEGG COMPOUND
Baicalein KEGG COMPOUND
Brand Name Source
Noroxylin ChemIDplus
Manual Xrefs Databases
3WL PDBeChem
4444924 ChemSpider
Baicalein Wikipedia
C00001022 KNApSAcK
C10023 KEGG COMPOUND
CN102429899 Patent
CPD-12724 MetaCyc
DB16101 DrugBank
FDB012057 FooDB
HMDB0134890 HMDB
LMPK12111095 LIPID MAPS
LSM-6355 LINCS
View more database links
Registry Numbers Types Sources
272683 Reaxys Registry Number Reaxys
272683 Beilstein Registry Number Beilstein
491-67-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
20 September 2021