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> Main
CHEBI:77570 - tropisetron hydrochloride
Main
ChEBI Ontology
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ChEBI Name
tropisetron hydrochloride
ChEBI ID
CHEBI:77570
Definition
A hydrochloride obtained by combining equimolar amounts of tropisetron and hydrogen chloride.
Stars
This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Read full article at Wikipedia
Formula
C17H21ClN2O2
Net Charge
0
Average Mass
320.81400
Monoisotopic Mass
320.12916
InChI
InChI=1S/C17H20N2O2.ClH/c1-
19-
11-
6-
7-
12(19)
9-
13(8-
11)
21-
17(20)
15-
10-
18-
16-
5-
3-
2-
4-
14(15)
16;/h2-
5,10-
13,18H,6-
9H2,1H3;1H/t11-
,12+,13+;
InChIKey
XIEGSJAEZIGKSA-LUNMCBQDSA-N
SMILES
Cl.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12
Roles Classification
Biological Role
(s):
apoptosis inhibitor
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
Application
(s):
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
immunomodulator
Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
nicotinic acetylcholine receptor agonist
An agonist that selectively binds to and activates a nicotinic acetylcholine receptor.
serotonergic antagonist
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
tropisetron hydrochloride (
CHEBI:77570
)
has part
tropisetron(1+) (
CHEBI:77571
)
tropisetron hydrochloride (
CHEBI:77570
)
has role
anti-inflammatory agent (
CHEBI:67079
)
tropisetron hydrochloride (
CHEBI:77570
)
has role
antiemetic (
CHEBI:50919
)
tropisetron hydrochloride (
CHEBI:77570
)
has role
apoptosis inhibitor (
CHEBI:68494
)
tropisetron hydrochloride (
CHEBI:77570
)
has role
immunomodulator (
CHEBI:50846
)
tropisetron hydrochloride (
CHEBI:77570
)
has role
neuroprotective agent (
CHEBI:63726
)
tropisetron hydrochloride (
CHEBI:77570
)
has role
nicotinic acetylcholine receptor agonist (
CHEBI:47958
)
tropisetron hydrochloride (
CHEBI:77570
)
has role
serotonergic antagonist (
CHEBI:48279
)
tropisetron hydrochloride (
CHEBI:77570
)
has role
trypanocidal drug (
CHEBI:36335
)
tropisetron hydrochloride (
CHEBI:77570
)
is a
hydrochloride (
CHEBI:36807
)
IUPAC Names
(3-
endo
)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1
H
-indole-3-carboxylate hydrochloride
(3-
endo
,8-
syn
)-
3-
[(1
H
-
indol-
3-
ylcarbonyl)oxy]-
8-
methyl-
8-
azoniabicyclo[3.2.1]octane chloride
Synonyms
Sources
Tropisetron HCl
ChemIDplus
Tropisetron monohydrochloride
ChemIDplus
Brand Name
Source
Navoban
KEGG DRUG
Manual Xrefs
Databases
CN101278921
Patent
CN101444508
Patent
CN1682721
Patent
D02041
KEGG DRUG
Tropisetron
Wikipedia
View more database links
Registry Numbers
Types
Sources
105826-92-4
CAS Registry Number
ChemIDplus
105826-92-4
CAS Registry Number
KEGG DRUG
11257467
Reaxys Registry Number
Reaxys
Citations
Types
Sources
12239690
PubMed citation
Europe PMC
16086881
PubMed citation
Europe PMC
17697550
PubMed citation
Europe PMC
17876159
PubMed citation
Europe PMC
21924384
PubMed citation
Europe PMC
23391849
PubMed citation
Europe PMC
Last Modified
04 March 2014