PH 797804 (CHEBI:82715)

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ChEBI Name	PH 797804

ChEBI ID	CHEBI:82715

Definition	A member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1-yl}-4-methylbenzoic acid with the amino group of methylamine.

Stars	This entity has been manually annotated by the ChEBI Team.

Submitter	Matthias Ziehm

Supplier Information

Download	Molfile XML SDF

Formula

C22H19BrF2N2O3

Net Charge

Average Mass

477.29900

Monoisotopic Mass

476.05471

InChI

InChI=1S/C22H19BrF2N2O3/c1-12-4-5-14(21(28)26-3)9-18(12)27-13(2)8-19(20(23)22(27)29)30-11-15-6-7-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28)

InChIKey

KCAJXIDMCNPGHZ-UHFFFAOYSA-N

SMILES

CNC(=O)c1ccc(C)c(c1)-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O

Roles Classification
Biological Role(s):	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).

Application(s):	anti-inflammatory agent Any compound that has anti-inflammatory effects.

ChEBI Ontology
Outgoing	PH 797804 (CHEBI:82715) has role anti-inflammatory agent (CHEBI:67079) PH 797804 (CHEBI:82715) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091) PH 797804 (CHEBI:82715) is a aromatic ether (CHEBI:35618) PH 797804 (CHEBI:82715) is a benzamides (CHEBI:22702) PH 797804 (CHEBI:82715) is a organobromine compound (CHEBI:37141) PH 797804 (CHEBI:82715) is a organofluorine compound (CHEBI:37143) PH 797804 (CHEBI:82715) is a pyridone (CHEBI:38183)

IUPAC Name

3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide

Synonyms	Sources
3-Bromo-4-((2,4-difluorobenzyl)oxy)-1-(5-((methylamino)carbonyl)-2-methylphenyl)-6-methylpyridin-2(1H)-one	ChemIDplus
PH-797804	ChemIDplus
PH797804	ChemIDplus

Last Modified

26 February 2016