InChI=1S/C17H14O7/c1-22-9-6-12(20)14-13(7-9)24-16(17(23-2)15(14)21)8-3-4-10(18)11(19)5-8/h3-7,18-20H,1-2H3 |
LUJAXSNNYBCFEE-UHFFFAOYSA-N |
COc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(OC)c2=O |
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EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of of 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+), EC 1.3.1.22, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5alpha-dihydrotestosterone.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
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View more via ChEBI Ontology
Outgoing
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3',4',5-trihydroxy-3,7-dimethoxyflavone
(CHEBI:18010)
has functional parent
quercetin
(CHEBI:16243)
3',4',5-trihydroxy-3,7-dimethoxyflavone
(CHEBI:18010)
has role
EC 1.3.1.22 [3-oxo-5α-steroid 4-dehydrogenase (NADP+)] inhibitor
(CHEBI:50781)
3',4',5-trihydroxy-3,7-dimethoxyflavone
(CHEBI:18010)
has role
metabolite
(CHEBI:25212)
3',4',5-trihydroxy-3,7-dimethoxyflavone
(CHEBI:18010)
is a
dimethoxyflavone
(CHEBI:23798)
3',4',5-trihydroxy-3,7-dimethoxyflavone
(CHEBI:18010)
is a
trihydroxyflavone
(CHEBI:27116)
3',4',5-trihydroxy-3,7-dimethoxyflavone
(CHEBI:18010)
is conjugate acid of
3',4',5-trihydroxy-3,7-dimethoxyflavone(1−)
(CHEBI:77710)
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Incoming
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3',4',5-trihydroxy-3,7-dimethoxyflavone(1−)
(CHEBI:77710)
is conjugate base of
3',4',5-trihydroxy-3,7-dimethoxyflavone
(CHEBI:18010)
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2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
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2-(3,4-Dihydroxyphenyl)-5-hydroxy-3,7-dimethoxy-4-benzopyrone
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ChemIDplus
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3',4',5-Trihydroxy-3,7-dimethoxyflavone
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KEGG COMPOUND
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3,7-Di-O-methylquercetin
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KEGG COMPOUND
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3,7-O-dimethylquercetin
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ChEBI
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2068-02-2
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CAS Registry Number
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KEGG COMPOUND
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2068-02-2
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CAS Registry Number
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ChemIDplus
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338444
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Reaxys Registry Number
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Reaxys
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19031255
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PubMed citation
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Europe PMC
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2632060
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PubMed citation
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Europe PMC
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