CHEBI:74728 - acriflavinium chloride

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name acriflavinium chloride
ChEBI ID CHEBI:74728
Definition A mixture of 3,6-diaminoacridine dihydrochloride and 3,6-diamino-10-methylacridinium chloride hydrochloride.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Biological Role(s): antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
intercalator
A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages.
Application(s): antiseptic drug
A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body).
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing acriflavinium chloride (CHEBI:74728) has part 3,6-diamino-10-methylacridinium chloride.HCl (CHEBI:74727)
acriflavinium chloride (CHEBI:74728) has part 3,6-diaminoacridine dihydrochloride (CHEBI:74723)
acriflavinium chloride (CHEBI:74728) has role antibacterial agent (CHEBI:33282)
acriflavinium chloride (CHEBI:74728) has role antineoplastic agent (CHEBI:35610)
acriflavinium chloride (CHEBI:74728) has role antiseptic drug (CHEBI:48218)
acriflavinium chloride (CHEBI:74728) has role carcinogenic agent (CHEBI:50903)
acriflavinium chloride (CHEBI:74728) has role intercalator (CHEBI:24853)
acriflavinium chloride (CHEBI:74728) is a mixture (CHEBI:60004)
INNs Sources
acriflavinii chloridum WHO MedNet
acriflavinium chloride WHO MedNet
chlorure d'acriflavinium WHO MedNet
cloruro de acriflavinio WHO MedNet
Synonyms Sources
acriflavine hydrochloride ChemIDplus
acriflavinium hydrochloride ChEBI
acrivinium chloride (rINN) ChEBI
Manual Xref Database
C19554 KEGG COMPOUND
View more database links
Registry Number Type Source
69235-50-3 CAS Registry Number KEGG COMPOUND
Last Modified
28 July 2014
General Comment
2013-07-16 Note that the nomenclature is confusing: although acriflavinium chloride is the recommended International Nonproprietary Name for this mixture of 3,6-diaminoacridine dihydrochloride and 3,6-diamino-10-methylacridinium chloride hydrochloride, the same name is also used by the British Pharmacopoeia for acriflavinium monochloride, which is a mixture of 3,6-diaminoacridine monohydrochloride and 3,6-diamino-10-methylacridinium chloride.