CHEBI:66182 - taiwanhomoflavone A

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ChEBI Name taiwanhomoflavone A
ChEBI ID CHEBI:66182
Definition A biflavonoid that is a dimer resulting from the coupling of 7,4'-dimethoxy-5-hydroxy-6-methylflavone and 5,7,4'-trihydroxyflavone resulting in a bond between C-3' of the methoxyphenyl ring and C-8 of the chromene ring respectively. Isolated from Cephalotaxus wilsoniana, it exhibits cytotoxic activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C33H24O10
Net Charge 0
Average Mass 580.53770
Monoisotopic Mass 580.13695
InChI InChI=1S/C33H24O10/c1-15-25(41-3)14-28-31(32(15)39)23(38)13-27(42-28)17-6-9-24(40-2)19(10-17)29-20(35)11-21(36)30-22(37)12-26(43-33(29)30)16-4-7-18(34)8-5-16/h4-14,34-36,39H,1-3H3
InChIKey BZHVWUXJPKVWAI-UHFFFAOYSA-N
SMILES COc1cc2oc(cc(=O)c2c(O)c1C)-c1ccc(OC)c(c1)-c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1
Metabolite of Species Details
Cephalotaxus wilsoniana (NCBI:txid50179) Found in twig (BTO:0001411). See: PubMed
Cephalotaxus wilsoniana (NCBI:txid50179) Found in stem (BTO:0001300). See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing taiwanhomoflavone A (CHEBI:66182) has role antineoplastic agent (CHEBI:35610)
taiwanhomoflavone A (CHEBI:66182) has role metabolite (CHEBI:25212)
taiwanhomoflavone A (CHEBI:66182) is a biaryl (CHEBI:64459)
taiwanhomoflavone A (CHEBI:66182) is a biflavonoid (CHEBI:50128)
taiwanhomoflavone A (CHEBI:66182) is a hydroxyflavone (CHEBI:24698)
taiwanhomoflavone A (CHEBI:66182) is a methoxyflavone (CHEBI:25241)
IUPAC Name
2-{3-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl]-4-methoxyphenyl}-5-hydroxy-7-methoxy-6-methyl-4H-chromen-4-one
Registry Number Type Source
8666542 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
10726874 PubMed citation Europe PMC
Last Modified
09 July 2013