CHEBI:131848 - fotemustine

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ChEBI Name fotemustine
ChEBI ID CHEBI:131848
Definition A racemate comprising equimolar amounts of (R)- and (S)-fotemustine. It is an alkylating agent used in the treatment of malignant melanoma.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Adriano Dekker
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Formula C9H19ClN3O5P
Net Charge 0
Average Mass 315.691
Monoisotopic Mass 315.07509
Roles Classification
Biological Role(s): alkylating agent
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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ChEBI Ontology
Outgoing fotemustine (CHEBI:131848) has part (R)-fotemustine (CHEBI:131853)
fotemustine (CHEBI:131848) has part (S)-fotemustine (CHEBI:131854)
fotemustine (CHEBI:131848) has role alkylating agent (CHEBI:22333)
fotemustine (CHEBI:131848) has role antineoplastic agent (CHEBI:35610)
fotemustine (CHEBI:131848) is a racemate (CHEBI:60911)
INNs Sources
fotemustina WHO MedNet
fotemustine WHO MedNet
fotémustine WHO MedNet
fotemustinum WHO MedNet
Synonyms Sources
(±)-diethyl (1-{[(2-chloroethyl)(nitroso)carbamoyl]amino}ethyl)phosphonate ChEBI
diethyl-1-(3-(2-chloroethyl)-3-nitrosoureido)ethylphosphonate ChemIDplus
rac-fotemustine ChEBI
S 10036 ChemIDplus
Servier-10036 ChemIDplus
Brand Names Sources
Muphoran KEGG DRUG
Mustoforan ChemIDplus
Manual Xrefs Databases
D07255 KEGG DRUG
Fotemustine Wikipedia
FR2536075 Patent
US4567169 Patent
View more database links
Registry Numbers Types Sources
8626774 Reaxys Registry Number Reaxys
92118-27-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017