ciclopirox olamine (CHEBI:31398)

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ChEBI Name	ciclopirox olamine

ChEBI ID	CHEBI:31398

Definition	The ethanolamine salt of ciclopirox. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections.

Stars	This entity has been manually annotated by the ChEBI Team.

Secondary ChEBI IDs	CHEBI:489955, CHEBI:566263

Supplier Information

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Formula

C14H24N2O3

Net Charge

Average Mass

268.35200

Monoisotopic Mass

268.17869

InChI

InChI=1S/C12H16NO2.C2H7NO/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10;3-1-2-4/h7-8,10H,2-6H2,1H3;4H,1-3H2/q-1;/p+1

InChIKey

HKUKJIQHPXYJTP-UHFFFAOYSA-O

SMILES

[NH3+]CCO.Cc1cc(C2CCCCC2)n([O-])c(=O)c1

Roles Classification
Biological Role(s):	antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. ferroptosis inhibitor Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. (via hydroxypyridone antifungal drug )

Application(s):	geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. antiseborrheic A drug or agent applied to the skin to control seborrhea or seborrheic dermatitis. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. (via hydroxypyridone antifungal drug )

ChEBI Ontology
Outgoing	ciclopirox olamine (CHEBI:31398) has part ciclopirox (CHEBI:453011) ciclopirox olamine (CHEBI:31398) has part ethanolaminium(1+) (CHEBI:57603) ciclopirox olamine (CHEBI:31398) has role antibacterial agent (CHEBI:33282) ciclopirox olamine (CHEBI:31398) has role antiseborrheic (CHEBI:59010) ciclopirox olamine (CHEBI:31398) has role ferroptosis inhibitor (CHEBI:173084) ciclopirox olamine (CHEBI:31398) has role geroprotector (CHEBI:176497) ciclopirox olamine (CHEBI:31398) is a hydroxypyridone antifungal drug (CHEBI:87130) ciclopirox olamine (CHEBI:31398) is a organoammonium salt (CHEBI:46850)

IUPAC Name

2-hydroxyethanaminium 6-cyclohexyl-4-methyl-2-oxopyridin-1(2H)-olate

Synonyms	Sources
ciclopirox ethanolamine salt	ChemIDplus
HOE 296	ChemIDplus
HOE-296	DrugBank

Last Modified

20 September 2021