CHEBI:134126 - picrotoxin

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ChEBI Name picrotoxin
ChEBI ID CHEBI:134126
Definition A mixture consisting of equimolar amounts of picrotoxinin and picrotin found in the climbing plant Anamirta cocculus.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Sabrina Toro
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Roles Classification
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
GABA antagonist
A compound that inhibits the action of gamma-aminobutyric acid.
Application(s): central nervous system stimulant
Any drug that enhances the activity of the central nervous system.
antidote to barbiturate poisoning
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of barbiturates.
GABA antagonist
A compound that inhibits the action of gamma-aminobutyric acid.
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ChEBI Ontology
Outgoing picrotoxin (CHEBI:134126) has part picrotin (CHEBI:8205)
picrotoxin (CHEBI:134126) has part picrotoxinin (CHEBI:8206)
picrotoxin (CHEBI:134126) has role antidote to barbiturate poisoning (CHEBI:134173)
picrotoxin (CHEBI:134126) has role central nervous system stimulant (CHEBI:35337)
picrotoxin (CHEBI:134126) has role GABA antagonist (CHEBI:65259)
picrotoxin (CHEBI:134126) has role plant metabolite (CHEBI:76924)
picrotoxin (CHEBI:134126) is a mixture (CHEBI:60004)
IUPAC Name
(1R,3R,5S,8S,9R,12S,13R,14R)-1-hydroxy-13-methyl-14-(prop-1-en-2-yl)-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione — (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.19,12.03,5.05,13]tetradecane-6,11-dione (1:1)
Synonyms Sources
Cocculin ChemIDplus
Cocculus ChemIDplus
Coques du levant ChemIDplus
picrotoxine ChemIDplus
picrotoxinin - picrotin (1:1) ChemIDplus
Manual Xrefs Databases
HMDB0014609 HMDB
Picrotoxin Wikipedia
View more database links
Registry Numbers Types Sources
124-87-8 CAS Registry Number NIST Chemistry WebBook
124-87-8 CAS Registry Number ChemIDplus
21526388 Reaxys Registry Number Reaxys
Last Modified
14 December 2016